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8 Citations (Scopus)

Unusual enolizations in 19-nor-3-ketosteroids

Abul-Hajj, Y. J., Jan 1 1985, In : Journal of the Chemical Society, Chemical Communications. 21, p. 1479-1481 3 p.

Research output: Contribution to journal › Article

Ketosteroids

Direction compound

3 Citations (Scopus)

Stereospecific Reduction of Steroidal 4-Ene-3β-ols with Hydrazine

Abul-Hajj, Y. J., Sep 1 1971, In : Journal of Organic Chemistry. 36, 18, 1 p.

Research output: Contribution to journal › Article

hydrazine

Androstenols

Androstanes

Hydrazines

Oxidation-Reduction

5 Citations (Scopus)

Effect of 11-oxygen function on the steric course of reduction of steroids by homogeneous catalytic hydrogenation

Abul-Hajj, Y. J., Jan 1 1971, In : Steroids. 18, 3, p. 281-287 7 p.

Research output: Contribution to journal › Article

Hydrogenation

Chlorides

Steroids

Oxygen

Catalysts

Catalytic reduction of 3β‐hydroxyandrost‐4‐ene‐17‐one with tritium. II. The distribution and configuration of label in 3β‐hydroxy‐5β‐androstane‐17‐one¹

Abul‐Hajj, Y. J., Jan 1 1971, In : Journal of Labelled Compounds. 7, 3, p. 261-268 8 p.

Research output: Contribution to journal › Article

Tritium

Labels

Chloranil

Halogenation

Radioactivity

3 Citations (Scopus)

Catalytic reduction of 3β‐hydroxyandrost‐4‐ene‐17‐one with tritium. I. The distribution and configuration of label in 3β‐hydroxy‐5α‐androstane‐17‐one (1)

Abul‐Hajj, Y. J., Jan 1 1971, In : Journal of Labelled Compounds. 7, 1, p. 33-39 7 p.

Research output: Contribution to journal › Article

Chloranil

Tritium

Radioactivity

Labels

Gases

5 Citations (Scopus)

Crystalline Diethylstilbestrol (DES) Quinone: Synthesis, X-ray Analysis, and Stability

Abul-Hajj, Y. J., Tabakovic, K., Ojala, W. H. & Gleason, W. B., May 1995, In : Journal of the American Chemical Society. 117, 20, p. 5600-5601 2 p.

Research output: Contribution to journal › Article

X ray analysis

X-Rays

Crystalline materials

diethylstilbestrol quinone

31 Citations (Scopus)

Stereospecificity of hydrogen transfer from NADPH by steroid Δ⁴-5α- and Δ⁴-5β-reductase

Abul-Hajj, Y. J., Sep 1972, In : Steroids. 20, 3, p. 215-222 8 p.

Research output: Contribution to journal › Article

Ketosteroids

NADP

Hydrogen

Oxidoreductases

Steroids

7 Citations (Scopus)

Microbial oxidation of ecdysones. A convenient preparation of rubrosterone

Tom, W. M., Abul-Hajj, Y. J. & Koreeda, M., Dec 1 1975, In : Journal of the Chemical Society, Chemical Communications. 1, p. 24-25 2 p.

Research output: Contribution to journal › Article

Ecdysone

Fusarium

Microorganisms

Oxidation

ponasterone A

12 Citations (Scopus)

Aromatase inhibition by 4-thiosubstituted-4-androstene-3,17-dione derivatives

Abul-Hajj, Y. J., Jan 1990, In : Journal of Steroid Biochemistry. 35, 1, p. 139-143 5 p.

Research output: Contribution to journal › Article

Aromatase

Androstenedione

Derivatives

Sulfhydryl Reagents

Enzymes

7 Citations (Scopus)

Stereochemistry of enzymic C-4,5 dehydrogenation of steroids

Abul-Hajj, Y. J., May 21 1971, In : Biochemical and Biophysical Research Communications. 43, 4, p. 766-770 5 p.

Research output: Contribution to journal › Article

Ketosteroids

Stereochemistry

Dehydrogenation

Hydrogen

Steroids

49 Citations (Scopus)

An Estrogen-Nucleic Acid Adduct. Electroreductive Intermolecular Coupling of 3, 4-Estrone-o-quinone and Adenine

Abul-Hajj, Y. J., Tabakovic, K. & Tabakovic, I., Jun 1995, In : Journal of the American Chemical Society. 117, 22, p. 6144-6145 2 p.

Research output: Contribution to journal › Article

Adenine

Nucleic Acids

Estrogens

1,5(10)-estradiene-3,4,17-trione

9 Citations (Scopus)

Reaction of Benzeneselenenyl Halides with 3-Keto Steroids. A Novel Method for a-Bromination

Abul-Hajj, Y. J., Jan 1 1986, In : Journal of Organic Chemistry. 51, 17, p. 3380-3382 3 p.

Research output: Contribution to journal › Article

Steroids

Oxidation

estrane-3,17-dione

11 Citations (Scopus)

Studies on the mechanism of action of the aromatase inhibitor, 4-Hydroxyandrostenedione

Abul-Hajj, Y. J., Jan 1 1983, In : Steroids. 41, 6, p. 783-790 8 p.

Research output: Contribution to journal › Article

Aromatase Inhibitors

NADP

Aromatization

Tritium

Microsomes

40 Citations (Scopus)

Synthesis and Evaluation of 4-(Substituted thio)-4-androstene-3,17-dione Derivatives as Potential Aromatase Inhibitors

Abul-Hajj, Y. J., Jan 1 1986, In : Journal of Medicinal Chemistry. 29, 4, p. 582-584 3 p.

Research output: Contribution to journal › Article

Aromatase Inhibitors

Androstenedione

Aromatase

Sulfhydryl Reagents

Enzymes

52 Citations (Scopus)

Microbial cleavage of zearalenone

El-Sharkawy, S. & Abul-Hajj, Y. J., Jan 1 1988, In : Xenobiotica. 18, 4, p. 365-371 7 p.

Research output: Contribution to journal › Article

Zearalenone

Gliocladium

Spectroscopic analysis

Fermentation

Hydrolysis

10 Citations (Scopus)

Probing the Hydrophobic Pocket of the Active Site of Aromatase with 4-Phenoxy-7α-(phenylthio)-4-androstene-3,17-dione

Liu, X. P., Lambert, D. M. & Abul-Hajj, Y. J., Sep 1 1995, In : Journal of Medicinal Chemistry. 38, 20, p. 4135-4138 4 p.

Research output: Contribution to journal › Article

Aromatase

Androstenedione

Catalytic Domain

4-phenoxy-7-phenylthio-4-androstene-3,17-dione

7 Citations (Scopus)

Aromatase inhibitors: Effect of ring A and ring B unsaturation on aromatase inhibition by 4-thiosubstituted derivatives of 4-androstene-3,17-dione

Abul-Hajj, Y. J., Liu, X. P. & Hedge, M., Jan 1 1995, In : Steroids. 60, 5, p. 423-427 5 p.

Research output: Contribution to journal › Article

Aromatase Inhibitors

Aromatase

Androstenedione

Derivatives

Assays

30 Citations (Scopus)

Failure of ascorbic acid to inhibit growth of transplantable and dimethylbenzanthracene induced rat mammary tumors

Abul-Hajj, Y. J. & Kelliher, M., Oct 1982, In : Cancer Letters. 17, 1, p. 67-73 7 p.

Research output: Contribution to journal › Article

Ascorbic Acid

9,10-Dimethyl-1,2-benzanthracene

Breast Neoplasms

Growth

Drinking Water

46 Citations (Scopus)

Microbiological Transformation of (±)-Flavanone and (±)-Isoflavanone¹

Ibrahim, A. R. & Abul-Hajj, Y. J., Jan 1 1990, In : Journal of Natural Products. 53, 3, p. 644-656 13 p.

Research output: Contribution to journal › Article

Metabolites

Flavones

Microorganisms

Isoflavones

Spectrum Analysis

4 Citations (Scopus)

Steroid Δ⁴-Reductase Activity in Hepatomas of Different Growth Rates

Houglum, J. E. & Abul-Hajj, Y. J., Jan 1 1974, In : Cancer Research. 34, 5, p. 938-941 4 p.

Research output: Contribution to journal › Article

Hepatocellular Carcinoma

Oxidoreductases

Steroids

Growth

Liver

36 Citations (Scopus)

Microbiological transformation of chromone, chromanone, and ring a hydroxyflavones

Abul-Hajj, Y. J., Jan 1 1990, In : Journal of Natural Products. 53, 6, p. 1471-1478 8 p.

Research output: Contribution to journal › Article

Chromones

Flavones

Aspergillus niger

Aspergillus

Metabolites

30 Citations (Scopus)

Microbiological transformation of flavone and isoflavone

Ibrahim, A. R. S. & Abul-Hajj, Y. J., Jan 1 1990, In : Xenobiotica. 20, 4, p. 363-373 11 p.

Research output: Contribution to journal › Article

flavone

Isoflavones

Fermentation

Spectroscopic analysis

Ethylene Glycol

50 Citations (Scopus)

Microbial Transformation of Zearalenone. 2. Reduction, Hydroxylation, and Methylation Products

El-Sharkawy, S. H. & Abul-Hajj, Y. J., Feb 1 1988, In : Journal of Organic Chemistry. 53, 3, p. 515-519 5 p.

Research output: Contribution to journal › Article

Zearalenone

Hydroxylation

Methylation

Metabolites

Estrogen Receptors

4 Citations (Scopus)

Metabolism of Estrogens in Hepatomas of Different Growth Rates

Abul-Hajj, Y. J. & Morris, H. P., Jan 1 1977, In : Cancer Research. 37, 4, p. 1083-1087.

Research output: Contribution to journal › Article

Hepatocellular Carcinoma

Estrogens

Mixed Function Oxygenases

Growth

Liver

10 Citations (Scopus)

The Pharmacokinetics of Antipyrine and Three of Its Metabolites in the Rabbit: Intravenous Administration of Pure Metabolites

St. Peter, J. V., Abul-Hajj, Y. J. & Awni, W. M., Dec 1991, In : Pharmaceutical Research: An Official Journal of the American Association of Pharmaceutical Scientists. 8, 12, p. 1470-1476 7 p.

Research output: Contribution to journal › Article

Antipyrine

Pharmacokinetics

Metabolites

Intravenous Administration

Rabbits

12 Citations (Scopus)

Synthesis and evaluation of 4-substituted-4-androstene-3,17-dione derivatives as aromatase inhibitors

Abul-Hajj, Y. J., Liu, X. P. & Hedge, M., Aug 1995, In : Journal of Steroid Biochemistry and Molecular Biology. 54, 3-4, p. 111-119 9 p.

Research output: Contribution to journal › Article

Aromatase Inhibitors

Androstenedione

Aromatase

Derivatives

Alkylation

6 Citations (Scopus)

6β-Propynyl-substituted steroids: Mechanism-based enzyme-activated irreversible inhibitors of aromatase

Akkani, A., Paterlini, G., Gleason, W. B., Ojala, W. H. & Abul-Hajj, Y. J., Oct 9 1997, In : Journal of Medicinal Chemistry. 40, 20, p. 3263-3270 8 p.

Research output: Contribution to journal › Article

Aromatase Inhibitors

Aromatase

Steroids

Androstenedione

Enzymes

3 Citations (Scopus)

Microbiological hydroxylation of 4-androstene-3,17-dione

Abul-Hajj, Y. J., Dec 1 1970, In : Lloydia. 33, 2, 1 p.

Research output: Contribution to journal › Comment/debate

Androstanes

17-ketosteroids

Infrared Rays

17-Ketosteroids

Hydroxylation

7 Citations (Scopus)

Correlation between urinary steroids and estrogen receptor content in women with early breast cancer

Abul-Hajj, Y. J., Jan 1 1977, In : European Journal of Cancer (1965). 13, 7, p. 749-752 4 p.

Research output: Contribution to journal › Article

17-Ketosteroids

Steroid Receptors

Estrogen Receptors

Breast Neoplasms

Neoplasms

14 Citations (Scopus)

Partial purification of antigen e from mixed stems and leaves of short ragweed plant

Shafiee, A., Staba, E. J. & Abul-Hajj, Y. J., Jan 1 1973, In : Journal of Pharmaceutical Sciences. 62, 10, p. 1654-1656 3 p.

Research output: Contribution to journal › Article

Ambrosia

Hepatitis B e Antigens

Pollen

Antigens

Disc Electrophoresis

12 Citations (Scopus)

Estrogen Quinones: Reaction with Propylamine

Khasnis, D. & Abul-Hajj, Y. J., Jan 1 1994, In : Chemical Research in Toxicology. 7, 1, p. 68-72 5 p.

Research output: Contribution to journal › Article

Propylamines

Quinones

Estrogens

Addition reactions

Oxazoles

21 Citations (Scopus)

Molecular modeling studies on 11β-aminoethoxyphenyl and 7α-aminoethoxyphenyl estradiols. evidence suggesting a common hydrophobic pocket in estrogen receptor

Poupaert, J. H., Lambert, D. M., Vamecq, J. & Abul-Hajj, Y. J., Apr 20 1995, In : Bioorganic and Medicinal Chemistry Letters. 5, 8, p. 839-842 4 p.

Research output: Contribution to journal › Article

Molecular modeling

Molecular Dynamics Simulation

Estrogen Receptors

Molecular dynamics

Estradiol

21 Citations (Scopus)

Reaction of Lysine with Estrone 3,4-o-Quinone

Tabakovic, K. & Abul-Hajj, Y. J., Sep 1 1994, In : Chemical Research in Toxicology. 7, 5, p. 696-701 6 p.

Research output: Contribution to journal › Article

Estrone

Complex Mixtures

Reaction products

Lysine

1,5(10)-estradiene-3,4,17-trione

8 Citations (Scopus)

Synthesis and biological activity of 17β -substituted estradiol

Xiaodong, Q. & Abul-Hajj, Y. J., Jun 1988, In : Journal of Steroid Biochemistry. 29, 6, p. 657-663 7 p.

Research output: Contribution to journal › Article

Bioactivity

Estradiol

Estradiol Receptors

Derivatives

Estrogen Receptor Modulators

30 Citations (Scopus)

Catechol estrogen adducts

Abul-Hajj, Y. J. & Cisek, P. L., Jul 1988, In : Journal of Steroid Biochemistry. 31, 1, p. 107-110 4 p.

Research output: Contribution to journal › Article

Catechol Estrogens

Glutathione

Hydroxyestrones

Tritium

Liver Microsomes

25 Citations (Scopus)

Reactions of 3,4-estrone quinone with mimics of amino acid side chains

Abul-Hajj, Y. J., Tabakovic, K., Gleason, W. B. & Ojala, W. H., Mar 1 1996, In : Chemical research in toxicology. 9, 2, p. 434-438 5 p.

Research output: Contribution to journal › Article

4-methylimidazole

Estrone

Amino Acids

Skatole

Acetic Acid

4 Citations (Scopus)

Etiocholanolone receptor in rat liver and novikoff rat hepatoma cell culture

Adigweme, A. I. & Abul-Hajj, Y. J., Jan 1 1981, In : Journal of Steroid Biochemistry. 14, 9, p. 867-875 9 p.

Research output: Contribution to journal › Article

Experimental Liver Neoplasms

Etiocholanolone

Cell culture

Liver

Rats

13 Citations (Scopus)

Synthesis and biologic activities of 11β-substituted estradiol as potential antiestrogens

Qian, X. & Abul-Hajj, Y. J., May 1990, In : Steroids. 55, 5, p. 238-241 4 p.

Research output: Contribution to journal › Article

Estrogen Receptor Modulators

Estrogen Receptors

Estradiol

Rats

Competitive Binding

15 Citations (Scopus)

Effect of catechol estrogens on rat mammary tumors

Abul-Hajj, Y. J., Dec 1 1979, In : Cancer Research. 39, 12, p. 4882-4886 5 p.

Research output: Contribution to journal › Article

Catechol Estrogens

Breast Neoplasms

Neoplasms

Growth

Estriol

13 Citations (Scopus)

Significance of lipoidal estradiol in human mammary tumors

Abul-Hajj, Y. J. & Nurieddin, A., Oct 1983, In : Steroids. 42, 4, p. 417-426 10 p.

Research output: Contribution to journal › Article

Tumors

Estradiol

Esters

Breast Neoplasms

Hydrolysis

5 Citations (Scopus)

Synthesis and biological activity of 4-methylestradiol

Qian, X. D. & Abul-Hajj, Y. J., May 1990, In : Journal of Steroid Biochemistry. 35, 6, p. 745-747 3 p.

Research output: Contribution to journal › Article

Androstadienes

Aromatization

Estrone

Bioactivity

Estradiol

28 Citations (Scopus)

Regioselective reaction of thiols with catechol estrogens and estrogen-O-quinones

Abul-Hajj, Y. J. & Cisek, P. L., Aug 1986, In : Journal of Steroid Biochemistry. 25, 2, p. 245-247 3 p.

Research output: Contribution to journal › Article

Catechol Estrogens

Quinones

Sulfhydryl Compounds

Estrogens

Sulfides

1 Citation (Scopus)

Altered Steroid Δ⁴-Reductase Activity in Mammary Tumor-bearing Rats

Abul-Hajj, Y. J., Apr 1 1981, In : Cancer Research. 41, 4, p. 1329-1333 5 p.

Research output: Contribution to journal › Article

Oxidoreductases

Steroids

Breast Neoplasms

Neoplasms

Liver

9 Citations (Scopus)

The effect of the aromatase inhibitor, 4-(phenylthio)-4-androstene-3,17-dione, on dimethylbenz(a)anthracene-induced rat mammary tumors

Abul-Hajj, Y. J., 1989, In : Journal of Steroid Biochemistry. 34, 1-6, p. 439-442 4 p.

Research output: Contribution to journal › Article

Aromatase Inhibitors

Rats

Tumors

Breast Neoplasms

Aromatase

3 Citations (Scopus)

Reaction of thiol nucleophiles with 1,2-epoxy- and 4,5-epoxy-estrene-3-one-17β-ols

Ghaffari, M. A. & Abul-Hajj, Y. J., Oct 1990, In : Journal of Steroid Biochemistry and Molecular Biology. 37, 2, p. 237-244 8 p.

Research output: Contribution to journal › Article

Nucleophiles

Sulfhydryl Compounds

Epoxy Compounds

Dehydration

Catechol Estrogens

40 Citations (Scopus)

Transformation of Steroids by Algae

Abul-Hajj, Y. J. & Qian, X., Jan 1 1986, In : Journal of Natural Products. 49, 2, p. 244-248 5 p.

Research output: Contribution to journal › Article

Androstenes

Tics

Androstenedione

Algae

Testosterone

38 Citations (Scopus)

Potent growth inhibitory activity of zidovudine on cultured human breast cancer cells and rat mammary tumors

Wagner, C. R., Ballato, G., Akanni, A. O., McIntee, E. J., Larson, R. S., Chang, S. L. & Abul-Hajj, Y. J., Jun 15 1997, In : Cancer Research. 57, 12, p. 2341-2345 5 p.

Research output: Contribution to journal › Article

Zidovudine

Breast Neoplasms

Growth

Inhibitory Concentration 50

T-Cell Leukemia

27 Citations (Scopus)

Estrogen-nucleic acid adducts: Guanine is major site for interaction between 3,4-estrone quinone and COIII gene

Roy, D. & Abul-Hajj, Y. J., Jun 1 1997, In : Carcinogenesis. 18, 6, p. 1247-1249 3 p.

Research output: Contribution to journal › Article

Estrone

Guanine

Nucleic Acids

Estrogens

Genes

12 Citations (Scopus)

Effect of estrogens on β-hydroxy-β-methylglutaryl coenzyme a reductase activity and cholesterol levels

Abul-Hajj, Y. J., Jun 1981, In : Steroids. 37, 6, p. 601-607 7 p.

Research output: Contribution to journal › Article

Coenzymes

Oxidoreductases

Estrogens

Cholesterol

Nutrition

33 Citations (Scopus)

Estrogen-nucleic acid adducts: Dissection of the reaction of 3,4-estrone quinone and its radical anion and radical cation with deoxynucleosides and DNA

Akanni, A. & Abul-Hajj, Y. J., Dec 1 1999, In : Chemical research in toxicology. 12, 12, p. 1247-1253 7 p.

Research output: Contribution to journal › Article

Dissection

Estrone

Nucleic Acids

Anions

Cations