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8 Citations (Scopus)

Unusual enolizations in 19-nor-3-ketosteroids

Abul-Hajj, Y. J., Jan 1 1985, In : Journal of the Chemical Society, Chemical Communications. 21, p. 1479-1481 3 p.

Research output: Contribution to journalArticle

Ketosteroids
Direction compound
3 Citations (Scopus)

Stereospecific Reduction of Steroidal 4-Ene-3β-ols with Hydrazine

Abul-Hajj, Y. J., Sep 1 1971, In : Journal of Organic Chemistry. 36, 18, 1 p.

Research output: Contribution to journalArticle

hydrazine
Androstenols
Androstanes
Hydrazines
Oxidation-Reduction
5 Citations (Scopus)

Effect of 11-oxygen function on the steric course of reduction of steroids by homogeneous catalytic hydrogenation

Abul-Hajj, Y. J., Jan 1 1971, In : Steroids. 18, 3, p. 281-287 7 p.

Research output: Contribution to journalArticle

Hydrogenation
Chlorides
Steroids
Oxygen
Catalysts
Tritium
Labels
Chloranil
Halogenation
Radioactivity
3 Citations (Scopus)
Chloranil
Tritium
Radioactivity
Labels
Gases
5 Citations (Scopus)

Crystalline Diethylstilbestrol (DES) Quinone: Synthesis, X-ray Analysis, and Stability

Abul-Hajj, Y. J., Tabakovic, K., Ojala, W. H. & Gleason, W. B., May 1995, In : Journal of the American Chemical Society. 117, 20, p. 5600-5601 2 p.

Research output: Contribution to journalArticle

X ray analysis
X-Rays
Crystalline materials
diethylstilbestrol quinone
31 Citations (Scopus)

Stereospecificity of hydrogen transfer from NADPH by steroid Δ4-5α- and Δ4-5β-reductase

Abul-Hajj, Y. J., Sep 1972, In : Steroids. 20, 3, p. 215-222 8 p.

Research output: Contribution to journalArticle

Ketosteroids
NADP
Hydrogen
Oxidoreductases
Steroids
7 Citations (Scopus)

Microbial oxidation of ecdysones. A convenient preparation of rubrosterone

Tom, W. M., Abul-Hajj, Y. J. & Koreeda, M., Dec 1 1975, In : Journal of the Chemical Society, Chemical Communications. 1, p. 24-25 2 p.

Research output: Contribution to journalArticle

Ecdysone
Fusarium
Microorganisms
Oxidation
ponasterone A
12 Citations (Scopus)

Aromatase inhibition by 4-thiosubstituted-4-androstene-3,17-dione derivatives

Abul-Hajj, Y. J., Jan 1990, In : Journal of Steroid Biochemistry. 35, 1, p. 139-143 5 p.

Research output: Contribution to journalArticle

Aromatase
Androstenedione
Derivatives
Sulfhydryl Reagents
Enzymes
7 Citations (Scopus)

Stereochemistry of enzymic C-4,5 dehydrogenation of steroids

Abul-Hajj, Y. J., May 21 1971, In : Biochemical and Biophysical Research Communications. 43, 4, p. 766-770 5 p.

Research output: Contribution to journalArticle

Ketosteroids
Stereochemistry
Dehydrogenation
Hydrogen
Steroids
49 Citations (Scopus)

An Estrogen-Nucleic Acid Adduct. Electroreductive Intermolecular Coupling of 3, 4-Estrone-o-quinone and Adenine

Abul-Hajj, Y. J., Tabakovic, K. & Tabakovic, I., Jun 1995, In : Journal of the American Chemical Society. 117, 22, p. 6144-6145 2 p.

Research output: Contribution to journalArticle

Adenine
Nucleic Acids
Estrogens
1,5(10)-estradiene-3,4,17-trione
9 Citations (Scopus)

Reaction of Benzeneselenenyl Halides with 3-Keto Steroids. A Novel Method for a-Bromination

Abul-Hajj, Y. J., Jan 1 1986, In : Journal of Organic Chemistry. 51, 17, p. 3380-3382 3 p.

Research output: Contribution to journalArticle

Steroids
Oxidation
estrane-3,17-dione
11 Citations (Scopus)

Studies on the mechanism of action of the aromatase inhibitor, 4-Hydroxyandrostenedione

Abul-Hajj, Y. J., Jan 1 1983, In : Steroids. 41, 6, p. 783-790 8 p.

Research output: Contribution to journalArticle

Aromatase Inhibitors
NADP
Aromatization
Tritium
Microsomes
40 Citations (Scopus)

Synthesis and Evaluation of 4-(Substituted thio)-4-androstene-3,17-dione Derivatives as Potential Aromatase Inhibitors

Abul-Hajj, Y. J., Jan 1 1986, In : Journal of Medicinal Chemistry. 29, 4, p. 582-584 3 p.

Research output: Contribution to journalArticle

Aromatase Inhibitors
Androstenedione
Aromatase
Sulfhydryl Reagents
Enzymes
52 Citations (Scopus)

Microbial cleavage of zearalenone

El-Sharkawy, S. & Abul-Hajj, Y. J., Jan 1 1988, In : Xenobiotica. 18, 4, p. 365-371 7 p.

Research output: Contribution to journalArticle

Zearalenone
Gliocladium
Spectroscopic analysis
Fermentation
Hydrolysis
10 Citations (Scopus)

Probing the Hydrophobic Pocket of the Active Site of Aromatase with 4-Phenoxy-7α-(phenylthio)-4-androstene-3,17-dione

Liu, X. P., Lambert, D. M. & Abul-Hajj, Y. J., Sep 1 1995, In : Journal of Medicinal Chemistry. 38, 20, p. 4135-4138 4 p.

Research output: Contribution to journalArticle

Aromatase
Androstenedione
Catalytic Domain
4-phenoxy-7-phenylthio-4-androstene-3,17-dione
7 Citations (Scopus)

Aromatase inhibitors: Effect of ring A and ring B unsaturation on aromatase inhibition by 4-thiosubstituted derivatives of 4-androstene-3,17-dione

Abul-Hajj, Y. J., Liu, X. P. & Hedge, M., Jan 1 1995, In : Steroids. 60, 5, p. 423-427 5 p.

Research output: Contribution to journalArticle

Aromatase Inhibitors
Aromatase
Androstenedione
Derivatives
Assays
30 Citations (Scopus)

Failure of ascorbic acid to inhibit growth of transplantable and dimethylbenzanthracene induced rat mammary tumors

Abul-Hajj, Y. J. & Kelliher, M., Oct 1982, In : Cancer Letters. 17, 1, p. 67-73 7 p.

Research output: Contribution to journalArticle

Ascorbic Acid
9,10-Dimethyl-1,2-benzanthracene
Breast Neoplasms
Growth
Drinking Water
46 Citations (Scopus)

Microbiological Transformation of (±)-Flavanone and (±)-Isoflavanone1

Ibrahim, A. R. & Abul-Hajj, Y. J., Jan 1 1990, In : Journal of Natural Products. 53, 3, p. 644-656 13 p.

Research output: Contribution to journalArticle

Metabolites
Flavones
Microorganisms
Isoflavones
Spectrum Analysis
4 Citations (Scopus)

Steroid Δ4-Reductase Activity in Hepatomas of Different Growth Rates

Houglum, J. E. & Abul-Hajj, Y. J., Jan 1 1974, In : Cancer Research. 34, 5, p. 938-941 4 p.

Research output: Contribution to journalArticle

Hepatocellular Carcinoma
Oxidoreductases
Steroids
Growth
Liver
36 Citations (Scopus)

Microbiological transformation of chromone, chromanone, and ring a hydroxyflavones

Abul-Hajj, Y. J., Jan 1 1990, In : Journal of Natural Products. 53, 6, p. 1471-1478 8 p.

Research output: Contribution to journalArticle

Chromones
Flavones
Aspergillus niger
Aspergillus
Metabolites
30 Citations (Scopus)

Microbiological transformation of flavone and isoflavone

Ibrahim, A. R. S. & Abul-Hajj, Y. J., Jan 1 1990, In : Xenobiotica. 20, 4, p. 363-373 11 p.

Research output: Contribution to journalArticle

flavone
Isoflavones
Fermentation
Spectroscopic analysis
Ethylene Glycol
50 Citations (Scopus)

Microbial Transformation of Zearalenone. 2. Reduction, Hydroxylation, and Methylation Products

El-Sharkawy, S. H. & Abul-Hajj, Y. J., Feb 1 1988, In : Journal of Organic Chemistry. 53, 3, p. 515-519 5 p.

Research output: Contribution to journalArticle

Zearalenone
Hydroxylation
Methylation
Metabolites
Estrogen Receptors
4 Citations (Scopus)

Metabolism of Estrogens in Hepatomas of Different Growth Rates

Abul-Hajj, Y. J. & Morris, H. P., Jan 1 1977, In : Cancer Research. 37, 4, p. 1083-1087.

Research output: Contribution to journalArticle

Hepatocellular Carcinoma
Estrogens
Mixed Function Oxygenases
Growth
Liver
10 Citations (Scopus)
Antipyrine
Pharmacokinetics
Metabolites
Intravenous Administration
Rabbits
12 Citations (Scopus)

Synthesis and evaluation of 4-substituted-4-androstene-3,17-dione derivatives as aromatase inhibitors

Abul-Hajj, Y. J., Liu, X. P. & Hedge, M., Aug 1995, In : Journal of Steroid Biochemistry and Molecular Biology. 54, 3-4, p. 111-119 9 p.

Research output: Contribution to journalArticle

Aromatase Inhibitors
Androstenedione
Aromatase
Derivatives
Alkylation
6 Citations (Scopus)

6β-Propynyl-substituted steroids: Mechanism-based enzyme-activated irreversible inhibitors of aromatase

Akkani, A., Paterlini, G., Gleason, W. B., Ojala, W. H. & Abul-Hajj, Y. J., Oct 9 1997, In : Journal of Medicinal Chemistry. 40, 20, p. 3263-3270 8 p.

Research output: Contribution to journalArticle

Aromatase Inhibitors
Aromatase
Steroids
Androstenedione
Enzymes
3 Citations (Scopus)

Microbiological hydroxylation of 4-androstene-3,17-dione

Abul-Hajj, Y. J., Dec 1 1970, In : Lloydia. 33, 2, 1 p.

Research output: Contribution to journalComment/debate

Androstanes
17-ketosteroids
Infrared Rays
17-Ketosteroids
Hydroxylation
7 Citations (Scopus)

Correlation between urinary steroids and estrogen receptor content in women with early breast cancer

Abul-Hajj, Y. J., Jan 1 1977, In : European Journal of Cancer (1965). 13, 7, p. 749-752 4 p.

Research output: Contribution to journalArticle

17-Ketosteroids
Steroid Receptors
Estrogen Receptors
Breast Neoplasms
Neoplasms
14 Citations (Scopus)

Partial purification of antigen e from mixed stems and leaves of short ragweed plant

Shafiee, A., Staba, E. J. & Abul-Hajj, Y. J., Jan 1 1973, In : Journal of Pharmaceutical Sciences. 62, 10, p. 1654-1656 3 p.

Research output: Contribution to journalArticle

Ambrosia
Hepatitis B e Antigens
Pollen
Antigens
Disc Electrophoresis
12 Citations (Scopus)

Estrogen Quinones: Reaction with Propylamine

Khasnis, D. & Abul-Hajj, Y. J., Jan 1 1994, In : Chemical Research in Toxicology. 7, 1, p. 68-72 5 p.

Research output: Contribution to journalArticle

Propylamines
Quinones
Estrogens
Addition reactions
Oxazoles
21 Citations (Scopus)

Molecular modeling studies on 11β-aminoethoxyphenyl and 7α-aminoethoxyphenyl estradiols. evidence suggesting a common hydrophobic pocket in estrogen receptor

Poupaert, J. H., Lambert, D. M., Vamecq, J. & Abul-Hajj, Y. J., Apr 20 1995, In : Bioorganic and Medicinal Chemistry Letters. 5, 8, p. 839-842 4 p.

Research output: Contribution to journalArticle

Molecular modeling
Molecular Dynamics Simulation
Estrogen Receptors
Molecular dynamics
Estradiol
21 Citations (Scopus)

Reaction of Lysine with Estrone 3,4-o-Quinone

Tabakovic, K. & Abul-Hajj, Y. J., Sep 1 1994, In : Chemical Research in Toxicology. 7, 5, p. 696-701 6 p.

Research output: Contribution to journalArticle

Estrone
Complex Mixtures
Reaction products
Lysine
1,5(10)-estradiene-3,4,17-trione
8 Citations (Scopus)

Synthesis and biological activity of 17β -substituted estradiol

Xiaodong, Q. & Abul-Hajj, Y. J., Jun 1988, In : Journal of Steroid Biochemistry. 29, 6, p. 657-663 7 p.

Research output: Contribution to journalArticle

Bioactivity
Estradiol
Estradiol Receptors
Derivatives
Estrogen Receptor Modulators
30 Citations (Scopus)

Catechol estrogen adducts

Abul-Hajj, Y. J. & Cisek, P. L., Jul 1988, In : Journal of Steroid Biochemistry. 31, 1, p. 107-110 4 p.

Research output: Contribution to journalArticle

Catechol Estrogens
Glutathione
Hydroxyestrones
Tritium
Liver Microsomes
25 Citations (Scopus)

Reactions of 3,4-estrone quinone with mimics of amino acid side chains

Abul-Hajj, Y. J., Tabakovic, K., Gleason, W. B. & Ojala, W. H., Mar 1 1996, In : Chemical research in toxicology. 9, 2, p. 434-438 5 p.

Research output: Contribution to journalArticle

4-methylimidazole
Estrone
Amino Acids
Skatole
Acetic Acid
4 Citations (Scopus)

Etiocholanolone receptor in rat liver and novikoff rat hepatoma cell culture

Adigweme, A. I. & Abul-Hajj, Y. J., Jan 1 1981, In : Journal of Steroid Biochemistry. 14, 9, p. 867-875 9 p.

Research output: Contribution to journalArticle

Experimental Liver Neoplasms
Etiocholanolone
Cell culture
Liver
Rats
13 Citations (Scopus)

Synthesis and biologic activities of 11β-substituted estradiol as potential antiestrogens

Qian, X. & Abul-Hajj, Y. J., May 1990, In : Steroids. 55, 5, p. 238-241 4 p.

Research output: Contribution to journalArticle

Estrogen Receptor Modulators
Estrogen Receptors
Estradiol
Rats
Competitive Binding
15 Citations (Scopus)

Effect of catechol estrogens on rat mammary tumors

Abul-Hajj, Y. J., Dec 1 1979, In : Cancer Research. 39, 12, p. 4882-4886 5 p.

Research output: Contribution to journalArticle

Catechol Estrogens
Breast Neoplasms
Neoplasms
Growth
Estriol
13 Citations (Scopus)

Significance of lipoidal estradiol in human mammary tumors

Abul-Hajj, Y. J. & Nurieddin, A., Oct 1983, In : Steroids. 42, 4, p. 417-426 10 p.

Research output: Contribution to journalArticle

Tumors
Estradiol
Esters
Breast Neoplasms
Hydrolysis
5 Citations (Scopus)

Synthesis and biological activity of 4-methylestradiol

Qian, X. D. & Abul-Hajj, Y. J., May 1990, In : Journal of Steroid Biochemistry. 35, 6, p. 745-747 3 p.

Research output: Contribution to journalArticle

Androstadienes
Aromatization
Estrone
Bioactivity
Estradiol
28 Citations (Scopus)

Regioselective reaction of thiols with catechol estrogens and estrogen-O-quinones

Abul-Hajj, Y. J. & Cisek, P. L., Aug 1986, In : Journal of Steroid Biochemistry. 25, 2, p. 245-247 3 p.

Research output: Contribution to journalArticle

Catechol Estrogens
Quinones
Sulfhydryl Compounds
Estrogens
Sulfides
1 Citation (Scopus)

Altered Steroid Δ4-Reductase Activity in Mammary Tumor-bearing Rats

Abul-Hajj, Y. J., Apr 1 1981, In : Cancer Research. 41, 4, p. 1329-1333 5 p.

Research output: Contribution to journalArticle

Oxidoreductases
Steroids
Breast Neoplasms
Neoplasms
Liver
9 Citations (Scopus)
Aromatase Inhibitors
Rats
Tumors
Breast Neoplasms
Aromatase
3 Citations (Scopus)

Reaction of thiol nucleophiles with 1,2-epoxy- and 4,5-epoxy-estrene-3-one-17β-ols

Ghaffari, M. A. & Abul-Hajj, Y. J., Oct 1990, In : Journal of Steroid Biochemistry and Molecular Biology. 37, 2, p. 237-244 8 p.

Research output: Contribution to journalArticle

Nucleophiles
Sulfhydryl Compounds
Epoxy Compounds
Dehydration
Catechol Estrogens
40 Citations (Scopus)

Transformation of Steroids by Algae

Abul-Hajj, Y. J. & Qian, X., Jan 1 1986, In : Journal of Natural Products. 49, 2, p. 244-248 5 p.

Research output: Contribution to journalArticle

Androstenes
Tics
Androstenedione
Algae
Testosterone
38 Citations (Scopus)

Potent growth inhibitory activity of zidovudine on cultured human breast cancer cells and rat mammary tumors

Wagner, C. R., Ballato, G., Akanni, A. O., McIntee, E. J., Larson, R. S., Chang, S. L. & Abul-Hajj, Y. J., Jun 15 1997, In : Cancer Research. 57, 12, p. 2341-2345 5 p.

Research output: Contribution to journalArticle

Zidovudine
Breast Neoplasms
Growth
Inhibitory Concentration 50
T-Cell Leukemia
27 Citations (Scopus)

Estrogen-nucleic acid adducts: Guanine is major site for interaction between 3,4-estrone quinone and COIII gene

Roy, D. & Abul-Hajj, Y. J., Jun 1 1997, In : Carcinogenesis. 18, 6, p. 1247-1249 3 p.

Research output: Contribution to journalArticle

Estrone
Guanine
Nucleic Acids
Estrogens
Genes
12 Citations (Scopus)

Effect of estrogens on β-hydroxy-β-methylglutaryl coenzyme a reductase activity and cholesterol levels

Abul-Hajj, Y. J., Jun 1981, In : Steroids. 37, 6, p. 601-607 7 p.

Research output: Contribution to journalArticle

Coenzymes
Oxidoreductases
Estrogens
Cholesterol
Nutrition
33 Citations (Scopus)

Estrogen-nucleic acid adducts: Dissection of the reaction of 3,4-estrone quinone and its radical anion and radical cation with deoxynucleosides and DNA

Akanni, A. & Abul-Hajj, Y. J., Dec 1 1999, In : Chemical research in toxicology. 12, 12, p. 1247-1253 7 p.

Research output: Contribution to journalArticle

Dissection
Estrone
Nucleic Acids
Anions
Cations