Zinc-deficiency-induced retinal dysfunction in Crohn's disease

Craig J. McClain, Le Chu Su, Howard Gilbert, John D Cameron

Research output: Contribution to journalArticlepeer-review

22 Scopus citations


A patient with Crohn's disease and low serum zinc concentrations is presented who had markedly abnormal dark adaptation. Oral zinc supplementation produced an improvement in dark adaptation, and discontinuation of zinc therapy was associated with a worsening of dark adaptation. Serum vitamin A levels were normal throughout this period. We suggest that impaired retinal function is another manifestation of zinc deficiency in Crohn's disease that may be improved with zinc supplementation.

Original languageEnglish (US)
Pages (from-to)85-87
Number of pages3
JournalDigestive Diseases and Sciences
Issue number1
StatePublished - Jan 1 1983


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