You shall not pass! Unveiling the barriers for cohesin-mediated loop extrusion

Silvia Meyer-Nava; Juan Carlos Rivera-Mulia

doi:10.1016/j.molcel.2022.06.028

You shall not pass! Unveiling the barriers for cohesin-mediated loop extrusion

Silvia Meyer-Nava, Juan Carlos Rivera-Mulia

Research output: Contribution to journal › Comment/debate › peer-review

Abstract

Dequeker and colleagues performed elegant in vivo, in silico, and in vitro experiments to demonstrate that the MCM complex, an essential DNA replication factor, is an obstacle for the DNA loop formation by cohesin.

Original language	English (US)
Pages (from-to)	2541-2543
Number of pages	3
Journal	Molecular Cell
Volume	82
Issue number	14
DOIs	https://doi.org/10.1016/j.molcel.2022.06.028
State	Published - Jul 21 2022

Bibliographical note

Funding Information:
J.C.R.-M. is supported by funding from the National Institute of General Medical Sciences of the National Institutes of Health under award number R35GM137950.

Publisher Copyright:
© 2022 Elsevier Inc.

PubMed: MeSH publication types

Journal Article
Research Support, N.I.H., Extramural
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title = "You shall not pass! Unveiling the barriers for cohesin-mediated loop extrusion",

abstract = "Dequeker and colleagues performed elegant in vivo, in silico, and in vitro experiments to demonstrate that the MCM complex, an essential DNA replication factor, is an obstacle for the DNA loop formation by cohesin.",

author = "Silvia Meyer-Nava and Rivera-Mulia, {Juan Carlos}",

note = "Funding Information: J.C.R.-M. is supported by funding from the National Institute of General Medical Sciences of the National Institutes of Health under award number R35GM137950. Publisher Copyright: {\textcopyright} 2022 Elsevier Inc.",

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You shall not pass! Unveiling the barriers for cohesin-mediated loop extrusion

Abstract

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