XBP-1 specifically promotes IgM synthesis and secretion, but is dispensable for degradation of glycoproteins in primary B cells

Biochemistry, Genetics and Molecular Biology

• Secretion (Process) 100%
• Glycoprotein 100%
• X Box Binding Protein 1 100%
• B Cell 100%
• Immunoglobulin M 100%
• Intravenous Immunoglobulin 16%
• Major Histocompatibility Complex 8%
• T Cell Receptor 8%
• Light Chain 8%
• Protein Targeting 8%
• Immunoglobulin Producing Cell 8%
• Messenger RNA 8%
• Lipopolysaccharide 8%

Keyphrases

• Glycoprotein 100%
• Immunoglobulin M 100%
• Primary B Cells 100%
• X-box Binding Protein 1 (XBP1) 100%
• B Cells 33%
• Endoplasmic Reticulum 16%
• Translational Control 8%
• Protein Degradation 8%
• Immunoglobulin 8%
• Lipopolysaccharide 8%
• Immunoglobulin Light Chains 8%
• Plasma Cells 8%
• Protein Trafficking 8%
• Large Set 8%
• Major Histocompatibility Complex Molecules 8%
• US11 8%
• Endoplasmic Reticulum Proteins 8%