Worldwide Network for Blood and Marrow Transplantation (WBMT) recommendations for establishing a hematopoietic cell transplantation program (Part I): Minimum requirements and beyond

Marcelo C. Pasquini, Alok Srivastava, Syed Osman Ahmed, Mahmoud Aljurf, Yoshiko Atsuta, Carol Doleysh, Sebastian Galeano, Eliane Gluckman, Hildegard Greinix, Gregory Hale, Parameswaran Hari, Shahrukh K. Hashmi, Naynesh Kamani, Mary J. Laughlin, Dietger Niederwieser, Adriana Seber, Jeffrey Szer, John A. Snowden, Koen Van Biesen, Paula WatryDaniel J. Weisdorf, Jane Apperley

Research output: Contribution to journalArticle

Abstract

Hematopoietic cell transplantation (HCT) is a highly complex procedure that requires a dedicated multidisciplinary team to optimize its safety. In addition, institutions may have different needs regarding indications based on regional disease prevalence or may have an interest in developing specialized services. Yet, structured recommendations are not commonly available. Here, the Transplant Center and Recipient Issues Standing Committee for the Worldwide Network for Blood and Marrow Transplantation (WBMT) organized a structured review of all pertinent elements to establish a transplant program. First, we solicited components from committee members and grouped them in domains (infrastructure, staff, cell processing laboratory, blood banking, laboratory, radiology, pharmacy, HLA testing, ancillary services and quality). Subsequently, reviewers scored all elements on a 7-point scale, from an absolute requirement (score of 1) to not required (score of 7). An independent group of five experienced transplant physicians reviewed the rankings. Minimum requirements to establish any HCT program were identified among elements with mean score of ≤2.0, and specific elements for allogeneic and autologous HCT were identified. Mean scores >2.0–4.0 were classified as preferred recommendation, and mean scores of >4.0 to ≤7.0 were considered ideal recommendations for advanced and complex types of transplantation. This structured set of recommendations guides the prioritization of minimum requirements to establish a transplant program and to set the path for expansion and further development.

Original languageEnglish (US)
JournalHematology/ Oncology and Stem Cell Therapy
DOIs
StateAccepted/In press - Jan 1 2019

Fingerprint

Cell Transplantation
Transplantation
Bone Marrow
Transplants
Committee Membership
Blood Banks
Radiology
Physicians
Safety

Keywords

  • Autologous vs. allogeneic transplants
  • Transplant program requirements

PubMed: MeSH publication types

  • Journal Article

Cite this

Worldwide Network for Blood and Marrow Transplantation (WBMT) recommendations for establishing a hematopoietic cell transplantation program (Part I) : Minimum requirements and beyond. / Pasquini, Marcelo C.; Srivastava, Alok; Ahmed, Syed Osman; Aljurf, Mahmoud; Atsuta, Yoshiko; Doleysh, Carol; Galeano, Sebastian; Gluckman, Eliane; Greinix, Hildegard; Hale, Gregory; Hari, Parameswaran; Hashmi, Shahrukh K.; Kamani, Naynesh; Laughlin, Mary J.; Niederwieser, Dietger; Seber, Adriana; Szer, Jeffrey; Snowden, John A.; Van Biesen, Koen; Watry, Paula; Weisdorf, Daniel J.; Apperley, Jane.

In: Hematology/ Oncology and Stem Cell Therapy, 01.01.2019.

Research output: Contribution to journalArticle

Pasquini, MC, Srivastava, A, Ahmed, SO, Aljurf, M, Atsuta, Y, Doleysh, C, Galeano, S, Gluckman, E, Greinix, H, Hale, G, Hari, P, Hashmi, SK, Kamani, N, Laughlin, MJ, Niederwieser, D, Seber, A, Szer, J, Snowden, JA, Van Biesen, K, Watry, P, Weisdorf, DJ & Apperley, J 2019, 'Worldwide Network for Blood and Marrow Transplantation (WBMT) recommendations for establishing a hematopoietic cell transplantation program (Part I): Minimum requirements and beyond', Hematology/ Oncology and Stem Cell Therapy. https://doi.org/10.1016/j.hemonc.2019.08.001
Pasquini, Marcelo C. ; Srivastava, Alok ; Ahmed, Syed Osman ; Aljurf, Mahmoud ; Atsuta, Yoshiko ; Doleysh, Carol ; Galeano, Sebastian ; Gluckman, Eliane ; Greinix, Hildegard ; Hale, Gregory ; Hari, Parameswaran ; Hashmi, Shahrukh K. ; Kamani, Naynesh ; Laughlin, Mary J. ; Niederwieser, Dietger ; Seber, Adriana ; Szer, Jeffrey ; Snowden, John A. ; Van Biesen, Koen ; Watry, Paula ; Weisdorf, Daniel J. ; Apperley, Jane. / Worldwide Network for Blood and Marrow Transplantation (WBMT) recommendations for establishing a hematopoietic cell transplantation program (Part I) : Minimum requirements and beyond. In: Hematology/ Oncology and Stem Cell Therapy. 2019.
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AU - Hari, Parameswaran

AU - Hashmi, Shahrukh K.

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AU - Szer, Jeffrey

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