World Health Organization Group I Pulmonary Hypertension: Epidemiology and Pathophysiology

Research output: Contribution to journalReview article

29 Scopus citations

Abstract

Pulmonary arterial hypertension (PAH) is a debilitating disease characterized by pathologic remodeling of the resistance pulmonary arteries, ultimately leading to right ventricular (RV) failure and death. In this article we discuss the definition of PAH, the initial epidemiology based on the National Institutes of Health Registry, and the updated epidemiology gleaned from contemporary registries, pathogenesis of pulmonary vascular dysfunction and proliferation, and RV failure in PAH.

Original languageEnglish (US)
Pages (from-to)363-374
Number of pages12
JournalCardiology Clinics
Volume34
Issue number3
DOIs
StatePublished - Aug 1 2016

Keywords

  • Epidemiology
  • Pathophysiology
  • Pulmonary arterial hypertension
  • Pulmonary vasculature
  • Right ventricle

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