Workshop studies with monoclonal antibodies identifying a novel porcine differentiation antigen, SWC9

J. Dominguez, A. Ezquerra, F. Alonso, R. Bullido, K. McCullough, A. Summerfield, A. Bianchi, R. J. Zwart, Y. B. Kim, F. Blecha, S. Eicher, M. P. Murtaugh, M. Pampusch, K. Burger

Research output: Contribution to journalArticle

21 Scopus citations

Abstract

Two monoclonal antibodies (mAb) within cluster M4 of the myeloid section of the Second International Swine CD Workshop, C4 (No. 144) and PM18-7 (No. 192), showed reactivity with thymocytes and among cells of myelomonocytic origin with mature macrophages but not with monocytes and granulocytes. Both mAb recognize a protein showing two bands of 205 kDa and 130 kDa under both reducing and non-reducing conditions. Although epitope mapping with these mAb could not be performed, this cluster received the SWC9 designation.

Original languageEnglish (US)
Pages (from-to)343-349
Number of pages7
JournalVeterinary immunology and immunopathology
Volume60
Issue number3-4
DOIs
StatePublished - Jan 30 1998

Keywords

  • Differentiation antigen
  • Macrophage
  • Monoclonal antibody

Fingerprint Dive into the research topics of 'Workshop studies with monoclonal antibodies identifying a novel porcine differentiation antigen, SWC9'. Together they form a unique fingerprint.

  • Cite this

    Dominguez, J., Ezquerra, A., Alonso, F., Bullido, R., McCullough, K., Summerfield, A., Bianchi, A., Zwart, R. J., Kim, Y. B., Blecha, F., Eicher, S., Murtaugh, M. P., Pampusch, M., & Burger, K. (1998). Workshop studies with monoclonal antibodies identifying a novel porcine differentiation antigen, SWC9. Veterinary immunology and immunopathology, 60(3-4), 343-349. https://doi.org/10.1016/S0165-2427(97)00110-4