Why CD8+ T Cells Need Diversity When Growing Up

Research output: Contribution to journalShort surveypeer-review

10 Scopus citations

Abstract

A thymus-specific subunit of the proteasome, β5t, was previously described and shown to be essential for positive selection of CD8+ T cells. In this issue of Immunity, Nitta et al. (2010) suggest that β5t is essential because it alters the specific peptide-MHC complexes displayed by cortical epithelial cells.

Original languageEnglish (US)
Pages (from-to)5-6
Number of pages2
JournalImmunity
Volume32
Issue number1
DOIs
StatePublished - Jan 29 2010

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