Why CD8+ T Cells Need Diversity When Growing Up

Kristin A. Hogquist; Yan Xing

doi:10.1016/j.immuni.2010.01.005

Why CD8⁺ T Cells Need Diversity When Growing Up

Kristin A. Hogquist, Yan Xing

Research output: Contribution to journal › Short survey › peer-review

12 Scopus citations

Abstract

A thymus-specific subunit of the proteasome, β5t, was previously described and shown to be essential for positive selection of CD8⁺ T cells. In this issue of Immunity, Nitta et al. (2010) suggest that β5t is essential because it alters the specific peptide-MHC complexes displayed by cortical epithelial cells.

Original language	English (US)
Pages (from-to)	5-6
Number of pages	2
Journal	Immunity
Volume	32
Issue number	1
DOIs	https://doi.org/10.1016/j.immuni.2010.01.005
State	Published - Jan 29 2010

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Publisher link

10.1016/j.immuni.2010.01.005

Find It

Find It at U of M Libraries

Cite this

@article{5128ae11ecba4151a6188b49981181c6,

title = "Why CD8+ T Cells Need Diversity When Growing Up",

abstract = "A thymus-specific subunit of the proteasome, β5t, was previously described and shown to be essential for positive selection of CD8+ T cells. In this issue of Immunity, Nitta et al. (2010) suggest that β5t is essential because it alters the specific peptide-MHC complexes displayed by cortical epithelial cells.",

author = "Hogquist, {Kristin A.} and Yan Xing",

year = "2010",

month = jan,

day = "29",

doi = "10.1016/j.immuni.2010.01.005",

language = "English (US)",

volume = "32",

pages = "5--6",

journal = "Immunity",

issn = "1074-7613",

publisher = "Cell Press",

number = "1",

}

TY - JOUR

T1 - Why CD8+ T Cells Need Diversity When Growing Up

AU - Hogquist, Kristin A.

AU - Xing, Yan

PY - 2010/1/29

Y1 - 2010/1/29

N2 - A thymus-specific subunit of the proteasome, β5t, was previously described and shown to be essential for positive selection of CD8+ T cells. In this issue of Immunity, Nitta et al. (2010) suggest that β5t is essential because it alters the specific peptide-MHC complexes displayed by cortical epithelial cells.

AB - A thymus-specific subunit of the proteasome, β5t, was previously described and shown to be essential for positive selection of CD8+ T cells. In this issue of Immunity, Nitta et al. (2010) suggest that β5t is essential because it alters the specific peptide-MHC complexes displayed by cortical epithelial cells.

UR - http://www.scopus.com/inward/record.url?scp=74549185929&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=74549185929&partnerID=8YFLogxK

U2 - 10.1016/j.immuni.2010.01.005

DO - 10.1016/j.immuni.2010.01.005

M3 - Short survey

C2 - 20152164

AN - SCOPUS:74549185929

SN - 1074-7613

VL - 32

SP - 5

EP - 6

JO - Immunity

JF - Immunity

IS - 1

ER -