Abstract
A thymus-specific subunit of the proteasome, β5t, was previously described and shown to be essential for positive selection of CD8+ T cells. In this issue of Immunity, Nitta et al. (2010) suggest that β5t is essential because it alters the specific peptide-MHC complexes displayed by cortical epithelial cells.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 5-6 |
| Number of pages | 2 |
| Journal | Immunity |
| Volume | 32 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jan 29 2010 |
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Why CD8+ T Cells Need Diversity When Growing Up. / Hogquist, Kristin A; Xing, Yan.
In: Immunity, Vol. 32, No. 1, 29.01.2010, p. 5-6.Research output: Contribution to journal › Short survey
}
TY - JOUR
T1 - Why CD8+ T Cells Need Diversity When Growing Up
AU - Hogquist, Kristin A
AU - Xing, Yan
PY - 2010/1/29
Y1 - 2010/1/29
N2 - A thymus-specific subunit of the proteasome, β5t, was previously described and shown to be essential for positive selection of CD8+ T cells. In this issue of Immunity, Nitta et al. (2010) suggest that β5t is essential because it alters the specific peptide-MHC complexes displayed by cortical epithelial cells.
AB - A thymus-specific subunit of the proteasome, β5t, was previously described and shown to be essential for positive selection of CD8+ T cells. In this issue of Immunity, Nitta et al. (2010) suggest that β5t is essential because it alters the specific peptide-MHC complexes displayed by cortical epithelial cells.
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UR - http://www.scopus.com/inward/citedby.url?scp=74549185929&partnerID=8YFLogxK
U2 - 10.1016/j.immuni.2010.01.005
DO - 10.1016/j.immuni.2010.01.005
M3 - Short survey
C2 - 20152164
AN - SCOPUS:74549185929
VL - 32
SP - 5
EP - 6
JO - Immunity
JF - Immunity
SN - 1074-7613
IS - 1
ER -