Who benefits from an eHealth-based stress management intervention in advanced prostate cancer? Results from a randomized controlled trial

Roberto M. Benzo, Patricia I. Moreno, Blanca Noriega-Esquives, Amy K. Otto, Frank J. Penedo

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

Objective: Conduct a secondary analysis to examine the effects of a tablet-delivered, group-based cognitive-behavioral stress management (CBSM) intervention for reducing symptom burden among men with advanced prostate cancer (APC) and elevated baseline levels of symptom burden. Methods: A total of 192 men with APC were randomized to either a CBSM or a health promotion condition and followed for one year. Six analytical samples were included in our study, each including participants who reported elevated levels of burden for the corresponding outcome at baseline. Outcomes included five domains of symptom-related quality of life (urinary incontinence n = 98; urinary irritation n = 61; bowel function n = 43; sexual function n = 177; and hormonal function n = 149) and depression (n = 31). Repeated measures mixed models were used to detect within- and between-group changes in outcomes. Results: Regardless of condition, participants with elevated symptom burden or mild-to-severe depression showed short-term (6-month) improvements in urinary irritation, bowel function, hormonal function, and depression scores. Only participants in the CBSM condition showed short-term (6-month) improvements in urinary incontinence, and long-term (12-month) improvements in urinary irritation, bowel function, hormonal function, and depression scores. Conclusions: Our findings suggest that targeting a web-based CBSM intervention to recipients most likely to benefit (elevated levels of symptom burden) can improve several domains of symptom-related quality of life and depressive symptoms in men with APC.

Original languageEnglish (US)
Pages (from-to)2063-2073
Number of pages11
JournalPsycho-Oncology
Volume31
Issue number12
DOIs
StatePublished - Dec 2022
Externally publishedYes

Bibliographical note

Publisher Copyright:
© 2022 John Wiley & Sons Ltd.

Keywords

  • cognitive behavioral therapy
  • depression
  • erectile dysfunction
  • patient reported outcome measures
  • prostatic neoplasms
  • psycho-oncology
  • quality of life
  • telemedicine
  • urinary incontinence

PubMed: MeSH publication types

  • Randomized Controlled Trial
  • Journal Article
  • Research Support, N.I.H., Extramural

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