What other biologic and mechanical factors might contribute to osteolysis?

E. M. Greenfield, Joan Bechtold

Research output: Contribution to journalArticlepeer-review

41 Scopus citations

Abstract

An overwhelming consensus exists that wear particles are the primary driving force in aseptic loosening of orthopaedic implants. Nonetheless, considerable evidence has emerged demonstrating that various other factors can modulate the biologic activity of orthopaedic wear particles. Two of the most studied modulating factors are bacterial endotoxins and implant motion.

Original languageEnglish (US)
Pages (from-to)S56-62
JournalThe Journal of the American Academy of Orthopaedic Surgeons
Volume16 Suppl 1
DOIs
StatePublished - 2008

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