What Is Unique About Nanomedicine? The Significance of the Mesoscale

George Khushf, Ronald A. Siegel

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


Unlike drugs and medical devices, for which long standing and continuously improving quality assurance/quality control infrastructures exist, many nano-based products lack well-defined standards that are useful to manufacturers and regulators. Inherent variabilities in nanoparticle sizes and shapes, their large surface-to-volume ratios, and their mesoscale interactions with subcellular structures, suggest new complexities and challenges that must be met before widespread application of nanomedicines can be expected.

Original languageEnglish (US)
Pages (from-to)780-794
Number of pages15
JournalJournal of Law, Medicine and Ethics
Issue number4
StatePublished - Dec 2012


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