What Can Be Learned From Minimum 20-year Followup Studies of Knee Arthroplasty?

John J. Callaghan, Christopher T. Martin, Yubo Gao, Andrew J. Pugely, Steve S. Liu, Devon D. Goetz, Scott S. Kelley, Richard C. Johnston

Research output: Contribution to journalArticlepeer-review

17 Scopus citations


Background: Long-term evaluation of knee arthroplasty should provide relevant information concerning the durability and performance of the implant and the procedure. Because most arthroplasties are performed in older patients, most long-term followup studies have been performed in elderly cohorts and have had low patient survivorship to final followup; the degree to which attrition from patient deaths over time in these studies might influence their results has been poorly characterized.


Level of Evidence: Level III, therapeutic study. See Guidelines for Authors for a complete description of levels of evidence.

Methods: Two knee arthroplasty cohorts from a single orthopaedic practice were evaluated: a modular tibial tray (101 knees) and a rotating platform (119 knees) design. All patients were followed for a minimum of 20 years or until death (mean, 14.1 years; SD 5.0 years). Average age at surgery for both cohorts was > 70 years. The indications for the two cohorts were identical (functionally limiting knee pain) and was surgeon-specific (each surgeon performed all surgeries in that cohort). Revision rates through a competing risks analysis for implants and survivorship curves for patients were evaluated.

Results: Both of these elderly cohorts showed excellent implant survivorship at 20 years followup with only small differences in revision rates (6% revision versus 0% revision for the modular tibial tray and rotating platform, respectively). However, attrition from patient deaths was substantial and overall patient survivorship to 20-year followup was only 26%. Patient survivorship was significantly higher in patients < 65 years of age in both cohorts (54% versus 15%, p < 0.001 modular tray cohort, and 52% versus 26%, p = 0.002 rotating platform cohort). Furthermore, in the modular tray cohort, patients < 65 years had significantly higher revision rates (15% versus 3%, p = 0.0019).

Conclusions: These two cohorts demonstrate the durability of knee arthroplasty in older patients (the vast majority older than 65 years). Unfortunately, few patients lived to 20-year followup, thus introducing bias into the analysis. These data may be useful as a reference for the design of future prospective studies, and consideration should be given to enrolling younger patients to have robust numbers of living patients at long-term followup.

Original languageEnglish (US)
Pages (from-to)94-100
Number of pages7
JournalClinical orthopaedics and related research
Issue number1
StatePublished - Jan 2015

Bibliographical note

Publisher Copyright:
© 2014, The Association of Bone and Joint Surgeons®.


Dive into the research topics of 'What Can Be Learned From Minimum 20-year Followup Studies of Knee Arthroplasty?'. Together they form a unique fingerprint.

Cite this