TY - JOUR
T1 - Well-Differentiated Liposarcoma/Atypical Lipomatous Tumor of the Oral Cavity
T2 - Report of Three Cases and Review of the Literature
AU - Piperi, Evangelia
AU - Tosios, Konstantinos I.
AU - Nikitakis, Nikolaos G.
AU - Kyriakopoulos, Vasileios F.
AU - Tzerbos, Fotios
AU - Koutlas, Ioannis G.
AU - Sklavounou, Alexandra
PY - 2012/9
Y1 - 2012/9
N2 - Atypical Lipomatous Tumor/Well Differentiated Liposarcoma (ALT/WDLS) is a soft tissue sarcoma of intermediate malignant behavior, most frequently affecting the retroperitoneum and lower extremities. Oral liposarcomas are very rare neoplasms, the most common histological subtype being ALT/WDLS. In this study, three additional cases of ALT/WDLS located on the tongue (2 cases) and the lower lip (1 case), respectively, are described. Analysis of the salient clinicopathologic features of 63 oral ALT/WDLS cases previously reported in the English language literature, as well as of the 3 cases presented in this study, indicates that the indolent biologic behavior of this tumor justifies its designation as a locally spreading malignant neoplasm, affording a rather conservative surgical approach.
AB - Atypical Lipomatous Tumor/Well Differentiated Liposarcoma (ALT/WDLS) is a soft tissue sarcoma of intermediate malignant behavior, most frequently affecting the retroperitoneum and lower extremities. Oral liposarcomas are very rare neoplasms, the most common histological subtype being ALT/WDLS. In this study, three additional cases of ALT/WDLS located on the tongue (2 cases) and the lower lip (1 case), respectively, are described. Analysis of the salient clinicopathologic features of 63 oral ALT/WDLS cases previously reported in the English language literature, as well as of the 3 cases presented in this study, indicates that the indolent biologic behavior of this tumor justifies its designation as a locally spreading malignant neoplasm, affording a rather conservative surgical approach.
KW - Atypical lipoma
KW - Liposarcoma
KW - Oral neoplasms
KW - Soft tissue sarcoma
UR - http://www.scopus.com/inward/record.url?scp=84865550066&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84865550066&partnerID=8YFLogxK
U2 - 10.1007/s12105-011-0327-2
DO - 10.1007/s12105-011-0327-2
M3 - Review article
C2 - 22234501
AN - SCOPUS:84865550066
SN - 1936-055X
VL - 6
SP - 354
EP - 363
JO - Head and Neck Pathology
JF - Head and Neck Pathology
IS - 3
ER -
