Weight loss, skin rash, and cough following bone marrow transplantation for chronic myelogenous leukemia

R. P. Witherspoon, P. McGlave, J. B. Campbell, T. Sigley, K. V.I. Rolston

Research output: Contribution to journalArticlepeer-review

Abstract

JW, a 41-year-old apple orchard worker, presented to his local physician with cough, fever, and sputum prroduction of 2 days' duration. Six hours earlier JW had a shaking chill and began to notice right-sided chest pain when he coughed. He has been feeling progessively weak. When questioned, JW denied hemoptysis but reported that for the last month he has had a decreased appetite and has lost 8 pounds, approximately 6% of his body weight. The patient has been able to work in the orchard every day. Remarkable in JW's history is that, on a routine employment physical examination 2 years ago, he was diagnosed with chronic myelogenous leukemia. He was asymptomatic at the time. Fifteen months ago, he had a bone marrow transplant from a human lymphocyte antigen-matched older brother. The physical examination was remarkable for egophony and rales at the right lung base, a temperature of 39.0°C, and a respiratory rate of 22. JW had a dry mouth, and skin examination showed a dry scaly rash over his arms. The remainder of the examination was within normal limits. What is the best course of action for diagnosis and treatment for this patient?.

Original languageEnglish (US)
Pages (from-to)202-205
Number of pages4
JournalCancer Practice
Volume6
Issue number4
DOIs
StatePublished - Jul 27 1998

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