Weaknesses and pitfalls of using mice and rats in cancer chemoprevention studies

Keyphrases

• Chemoprevention 100%
• In Cancer 100%
• Cancer Prevention 100%
• Cancer Chemoprevention 100%
• Rodents 100%
• Chemically Induced Carcinogenesis 100%
• Carcinogenesis Models 100%
• Histology 50%
• Long-term Safety 50%
• Chemopreventive 50%
• Transgenic Mouse Model 50%
• Tumor 50%
• Tumor Cells 50%
• Metabolism 50%
• Cold Stress 50%
• Chemical Agents 50%
• Inducer 50%
• Ambient Temperature 50%
• Copy number 50%
• Metastasizing 50%
• Metabolic Tissues 50%
• Long Lifespan 50%
• Temporal Aspects 50%
• Spatial Aspect 50%
• Mortal 50%
• Chemical Carcinogens 50%
• Multiple Cell Types 50%
• Data Variability 50%
• Equivalent Test 50%
• Metabolic Organs 50%
• DNA Promoter 50%
• Short Lifetime 50%

Medicine and Dentistry

• Chemoprevention 100%
• Weakness 100%
• Transgene 100%
• Lifespan 60%
• Carcinogenesis 60%
• Promoter Region 60%
• Chemoprophylaxis 40%
• Cancer Prevention 40%
• Malignant Neoplasm 20%
• Transgenic Mouse 20%
• Neoplasm 20%
• Tumor Cell 20%
• Mouse Study 20%
• Carcinogen 20%

Pharmacology, Toxicology and Pharmaceutical Science

• Malignant Neoplasm 100%
• Weakness 100%
• Carcinogenesis 75%
• Neoplasm 50%
• Carcinogen 25%
• Transgenic Mouse 25%
• Mouse Model 25%
• Chemopreventive Agents 25%