Volumetric analysis of abdominal aortic aneurysm

Kevin M. Baskin, Catherine A.M.D. Kusnick, Susanne Shamsolkottabi, Elvira V. Lang, J. D. Corson, William Stanford, Brad H. Thompson, Eric A. Hoffman

Research output: Chapter in Book/Report/Conference proceedingConference contribution

15 Scopus citations


The purpose of this study was to develop a valid, reliable and accurate system of measurement of abdominal aortic aneurysms, using volumetric analysis of x-ray computed tomographic data. This study evaluates illustrative cases, and compares measurements of AAA phantoms, using standard 2D versus volumetric methods. To validate the volumetric analysis, four phantom aneurysms were constructed in a range of diameters (4.5 - 7.0 cm) which presents the greatest management challenge to the clinician. These phantoms were imaged using a Toshiba Xpress SX helical CT. Separate scans were obtained at conventional (10 mm × 10 mm) and thin slice (5 mm × 5 mm) collimations. The thin slices were reconstructed at 2 mm intervals. Data from each of the 96 scans were interpreted using a standard 2D approach, then analyzed using task-oriented volumetric software. We evaluate patient assessments, and compare greatest outer diameters of phantoms, by standard versus volumetric methods. Qualitative differences between solutions based on standard versus volumetric analysis of illustrative patient cases are substantial. Expert radiologists' standard measurements of phantom aneurysms are highly reliable (r 2 = 0.901 - 0.958; p < 0.001), but biased toward significant overestimation of aneurysm diameters in the range of clinical interest. For the same phantoms, volumetric analysis was both more reliable (r 2 = 0.986 - 0.996; p < 0.001), and more accurate, with no significant bias in the range of interest. Volumetric analysis promotes selection of more valid management strategies, by providing vital information not otherwise available, and allowing more reliable and accurate assessment of abdominal aortic aneurysms. It is particularly valuable in the presence of aortic tortuosity, vessel eccentricity, and uncertain involvement of critical vessels.

Original languageEnglish (US)
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
EditorsEric A. Hoffman
Number of pages15
StatePublished - 1996
Externally publishedYes
EventMedical Imaging 1996: Physiology and Function from Multidimensional Images - Newport Beach, CA, USA
Duration: Feb 11 1996Feb 13 1996

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
ISSN (Print)0277-786X


ConferenceMedical Imaging 1996: Physiology and Function from Multidimensional Images
CityNewport Beach, CA, USA


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