Vitamin D Levels Do Not Predict Risk of Metatarsal Fractures

Benjamin R. Williams, Avis J. Thomas, Rachel C. Collier, Troy J. Boffeli, Sarah A. Anderson

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


Introduction. In the literature, there is conflicting data regarding the relationship between vitamin D and fractures. Reports on the effects of vitamin D levels on pathologies of the foot and ankle are limited. The purpose of this study is to assess the prevalence of vitamin D insufficiency in patients who have sustained low-energy metatarsal fractures compared to foot or ankle sprains without osseous involvement. Methods. Between May 2012 and August 2014, vitamin D levels and demographic data were collected prospectively in a total of 99 patients; 71 with metatarsal fractures and 28 with sprains, both from a low-energy mechanism of injury. Data between the metatarsal fracture group and sprain group were compared through univariate and multivariate analyses. Results. Mean vitamin D in the fracture group was 26.9 ng/mL (range = 78.0-4.3), and in the sprain group it was 27.1 ng/mL (range = 64.1-8.3; P =.93). Vitamin D insufficiency (<30 ng/mL) was present in 47 (66%) of fracture patients and 20 (71%) of sprain patients (P =.81). Conclusion. A high incidence of hypovitaminosis D was seen in all foot and ankle patients. There was no difference in mean vitamin D level or incidence of vitamin D insufficiency between patients with metatarsal fractures or sprains resulting from similar low-energy mechanisms. Levels of Evidence: Level III: Prospective, case-control study.

Original languageEnglish (US)
Pages (from-to)37-43
Number of pages7
JournalFoot and Ankle Specialist
Issue number1
StatePublished - Feb 1 2018

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© 2017, © 2017 The Author(s).


  • 25-hydroxyvitamin D
  • hypovitaminosis
  • metatarsal fractures
  • vitamin D


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