TY - JOUR
T1 - Viruses in extreme environments, current overview, and biotechnological potential
AU - Gil, Jose F.
AU - Mesa, Victoria
AU - Estrada-Ortiz, Natalia
AU - Lopez-Obando, Mauricio
AU - Gómez, Andrés
AU - Plácido, Jersson
N1 - Publisher Copyright:
© 2021 by the authors. Licensee MDPI, Basel, Switzerland.
PY - 2021/1
Y1 - 2021/1
N2 - Virus research has advanced significantly since the discovery of the tobacco mosaic virus (TMV), the characterization of its infection mechanisms and the factors that determine their pathogenicity. However, most viral research has focused on pathogenic viruses to humans, animals and plants, which represent only a small fraction in the virosphere. As a result, the role of most viral genes, and the mechanisms of coevolution between mutualistic viruses, their host and their environ-ment, beyond pathogenicity, remain poorly understood. This review focuses on general aspects of viruses that interact with extremophile organisms, characteristics and examples of mechanisms of adaptation. Finally, this review provides an overview on how knowledge of extremophile viruses sheds light on the application of new tools of relevant use in modern molecular biology, discussing their value in a biotechnological context.
AB - Virus research has advanced significantly since the discovery of the tobacco mosaic virus (TMV), the characterization of its infection mechanisms and the factors that determine their pathogenicity. However, most viral research has focused on pathogenic viruses to humans, animals and plants, which represent only a small fraction in the virosphere. As a result, the role of most viral genes, and the mechanisms of coevolution between mutualistic viruses, their host and their environ-ment, beyond pathogenicity, remain poorly understood. This review focuses on general aspects of viruses that interact with extremophile organisms, characteristics and examples of mechanisms of adaptation. Finally, this review provides an overview on how knowledge of extremophile viruses sheds light on the application of new tools of relevant use in modern molecular biology, discussing their value in a biotechnological context.
KW - Archaeal viruses
KW - Bacterial viruses
KW - Eukaryotic viruses
KW - Extremophile viruses
KW - Virosphere
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U2 - 10.3390/v13010081
DO - 10.3390/v13010081
M3 - Review article
C2 - 33430116
AN - SCOPUS:85099887766
SN - 1999-4915
VL - 13
JO - Viruses
JF - Viruses
IS - 1
M1 - 81
ER -