TY - JOUR
T1 - Virus and immune responses
T2 - Lymphocytic choriomeningitis virus as a prototype model of viral pathogenesis
AU - Oldstone, M. B.A.
AU - Ahmed, R.
AU - Byrne, J.
AU - Buchmeier, M. J.
AU - Riviere, Y.
AU - Southern, P.
PY - 1985
Y1 - 1985
N2 - Several of the major advances in contemporary virology and immunology came about through the study of lymphocytic choriomeningitis virus and the infection it produces. Included are concepts in immunologic tolerance, virus-antibody immune complexes, cytotoxic T cell generation, H-2 restriction, virally-induced immunopathology and the cessation of infected cells differentiated function without their destruction as a cause of disease. These concepts are reviewed and brought up to date in this report.
AB - Several of the major advances in contemporary virology and immunology came about through the study of lymphocytic choriomeningitis virus and the infection it produces. Included are concepts in immunologic tolerance, virus-antibody immune complexes, cytotoxic T cell generation, H-2 restriction, virally-induced immunopathology and the cessation of infected cells differentiated function without their destruction as a cause of disease. These concepts are reviewed and brought up to date in this report.
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U2 - 10.1093/oxfordjournals.bmb.a072029
DO - 10.1093/oxfordjournals.bmb.a072029
M3 - Article
C2 - 3882190
AN - SCOPUS:0021955350
VL - 41
SP - 70
EP - 74
JO - British Medical Bulletin
JF - British Medical Bulletin
SN - 0007-1420
IS - 1
ER -