Viral-based gene transfer to the mammalian CNS for functional genomic studies

Christopher G. Janson; Scott W.J. McPhee; Paola Leone; Andrew Freese; Matthew J. During

doi:10.1016/S0166-2236(00)01954-8

Viral-based gene transfer to the mammalian CNS for functional genomic studies

Christopher G. Janson, Scott W.J. McPhee, Paola Leone, Andrew Freese, Matthew J. During

Research output: Contribution to journal › Review article › peer-review

42 Scopus citations

Abstract

A fundamental problem in neuroscience has been the creation of suitable in vivo model systems to study basic neurological phenomena and pathology of the central nervous system (CNS). Somatic cell genetic engineering with viral vectors provides a versatile tool to model normal brain physiology and a variety of neurological diseases.

Original language	English (US)
Pages (from-to)	706-712
Number of pages	7
Journal	Trends in Neurosciences
Volume	24
Issue number	12
DOIs	https://doi.org/10.1016/S0166-2236(00)01954-8
State	Published - Dec 1 2001
Externally published	Yes

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10.1016/S0166-2236(00)01954-8

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title = "Viral-based gene transfer to the mammalian CNS for functional genomic studies",

abstract = "A fundamental problem in neuroscience has been the creation of suitable in vivo model systems to study basic neurological phenomena and pathology of the central nervous system (CNS). Somatic cell genetic engineering with viral vectors provides a versatile tool to model normal brain physiology and a variety of neurological diseases.",

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AU - Freese, Andrew

AU - During, Matthew J.

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Viral-based gene transfer to the mammalian CNS for functional genomic studies

Abstract

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