Ethyl acrylate and acrylonitrile fail to undergo efficient Baylis- Hillman reaction with fluoral, but provide good yields of products with pentafluorobenzaldehyde. Alternately, unsubstituted and β-substituted [α- (ethoxycarbonyl)vinyl]aluminum react with perfluoroalkyl and -aryl aldehydes and ketones to provide the α-hydroxyalkenylated fluoro-organic compounds in good to excellent yields.
|Original language||English (US)|
|Number of pages||4|
|State||Published - Nov 26 1998|
Bibliographical noteFunding Information:
Acknowledgments. The financial assistance from the Purdue Borane Research Fund is gratefully acknowledged. We are thankful to Professor Herbert C. Brown for helpful discussions and encouragement.