Vinylalumination of fluoro-carbonyl compounds

P. Veeraraghavan Ramachandran, M. Venkat Ram Reddy, Michael T. Rudd, Javier Read De Alaniz

Research output: Contribution to journalArticlepeer-review

35 Scopus citations


Ethyl acrylate and acrylonitrile fail to undergo efficient Baylis- Hillman reaction with fluoral, but provide good yields of products with pentafluorobenzaldehyde. Alternately, unsubstituted and β-substituted [α- (ethoxycarbonyl)vinyl]aluminum react with perfluoroalkyl and -aryl aldehydes and ketones to provide the α-hydroxyalkenylated fluoro-organic compounds in good to excellent yields.

Original languageEnglish (US)
Pages (from-to)8791-8794
Number of pages4
JournalTetrahedron Letters
Issue number48
StatePublished - Nov 26 1998

Bibliographical note

Funding Information:
Acknowledgments. The financial assistance from the Purdue Borane Research Fund is gratefully acknowledged. We are thankful to Professor Herbert C. Brown for helpful discussions and encouragement.


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