Vesicoureteric Reflux in Sibships

D. T. UEHLING; R. E. VLACH; R. M. PAULI; A. L. FRIEDMAN

doi:10.1111/j.1464-410X.1992.tb15604.x

Vesicoureteric Reflux in Sibships

D. T. UEHLING, R. E. VLACH, R. M. PAULI, A. L. FRIEDMAN

Pediatrics

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Abstract

Summary— A family with 4 of 6 siblings manifesting vesicoureteric reflux is presented. Reflux could not be demonstrated in preceding and succeeding generations in this family. Genetic analysis suggests that most instances of familial vesicoureteric reflux arise secondary to expression of autosomal dominant single genes with incomplete penetrance. Screening of sibships for reflux might be most appropriately carried out by urine analysis, culture and ultrasound imaging.

Original language	English (US)
Pages (from-to)	534-537
Number of pages	4
Journal	British Journal of Urology
Volume	69
Issue number	5
DOIs	https://doi.org/10.1111/j.1464-410X.1992.tb15604.x
State	Published - May 1992

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title = "Vesicoureteric Reflux in Sibships",

abstract = "Summary— A family with 4 of 6 siblings manifesting vesicoureteric reflux is presented. Reflux could not be demonstrated in preceding and succeeding generations in this family. Genetic analysis suggests that most instances of familial vesicoureteric reflux arise secondary to expression of autosomal dominant single genes with incomplete penetrance. Screening of sibships for reflux might be most appropriately carried out by urine analysis, culture and ultrasound imaging.",

author = "UEHLING, {D. T.} and VLACH, {R. E.} and PAULI, {R. M.} and FRIEDMAN, {A. L.}",

year = "1992",

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AU - UEHLING, D. T.

AU - VLACH, R. E.

AU - PAULI, R. M.

AU - FRIEDMAN, A. L.

PY - 1992/5

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N2 - Summary— A family with 4 of 6 siblings manifesting vesicoureteric reflux is presented. Reflux could not be demonstrated in preceding and succeeding generations in this family. Genetic analysis suggests that most instances of familial vesicoureteric reflux arise secondary to expression of autosomal dominant single genes with incomplete penetrance. Screening of sibships for reflux might be most appropriately carried out by urine analysis, culture and ultrasound imaging.

AB - Summary— A family with 4 of 6 siblings manifesting vesicoureteric reflux is presented. Reflux could not be demonstrated in preceding and succeeding generations in this family. Genetic analysis suggests that most instances of familial vesicoureteric reflux arise secondary to expression of autosomal dominant single genes with incomplete penetrance. Screening of sibships for reflux might be most appropriately carried out by urine analysis, culture and ultrasound imaging.

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ER -

Vesicoureteric Reflux in Sibships

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