Versatility of distributed focus ultrasound in treatment of superficial lesions

P. D. Higgins, X. W. Zeng, J. A. Zagzebski, B. R. Paliwal, R. A. Steeves

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


In order to study the efficacy of hyperthermia as a cancer treatment modality, it is important to be able to define the specific volume being raised to hyperthermic temperatures corresponding to the selected method of heating. Measurements have been made of temperature distributions in rat mammary tumors during steady state heating with annular focused ultrasound (2.0 MHz). Biological response in terms of growth inhibition is compared with uniformity of induced temperature throughout the tumors as a function of annular focusing dimensions.

Original languageEnglish (US)
Pages (from-to)1923-1931
Number of pages9
JournalInternational Journal of Radiation Oncology, Biology, Physics
Issue number10
StatePublished - Oct 1984

Bibliographical note

Copyright 2014 Elsevier B.V., All rights reserved.


  • Focused ultrasound
  • Hyperthermia
  • Temperature distribution


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