Ventricular septal defect following mitral valve replacement

Jose Arriola-Montenegro, Rishabh Tandon, Andrew Shaffer, Prabhjot S. Nijjar

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


Mitral valve surgery (MVS), with repair preferred to replacement, is a common procedure for the treatment of severe primary mitral regurgitation related to leaflet prolapse. Structural complications after MVS include left ventricular outflow obstruction, paravalvular leak and atrial septal defect. Intraoperative transoesophageal echocardiography and predischarge transthoracic echocardiography (TTE) specifically screen for these complications. Ventricular septal defect (VSD), a known complication after aortic valve surgery, is rarely reported after MVS. Recently, unsuccessful valvuloplasty prior to replacement was suggested as a risk factor. We present such a case and explore mechanisms with advanced cardiac imaging. In this case, the patient was found to have an elongated membranous septum that likely predisposed her to septal injury. Finally, we provide guidance on specific transoesophageal/transthoracic echocardiography views to avoid a missed diagnosis.

Original languageEnglish (US)
Article numberezae029
JournalEuropean Journal of Cardio-thoracic Surgery
Issue number2
StatePublished - Feb 1 2024

Bibliographical note

Publisher Copyright:
© The Author(s) 2024. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery. All rights reserved.


  • VSD
  • membranous septum
  • mitral valve replacement
  • mitral valve surgery
  • ventricular septal defect

PubMed: MeSH publication types

  • Journal Article


Dive into the research topics of 'Ventricular septal defect following mitral valve replacement'. Together they form a unique fingerprint.

Cite this