Purpose: The purpose of this study was to quantify and characterize venous valves within the major left ventricular (LV) veins of human hearts. Methods: Fiberscope cameras were inserted into the coronary sinus and were manipulated to major LV coronary veins of perfusion fixed human hearts (n=26). Observed venous valves were categorized by type and location and compared among the major LV veins. Results: Discernible venous valves were present in 23 of 26 examined hearts (89%); altogether, 105 valves were identified. Sixty-one of the valves were observed at the ostia to smaller branch veins (58% of all valves observed). Conclusions: Coronary venous valves could hinder or aid in the advancement of guide wires, catheters, and/or the placement of leads for a variety of cardiac interventional procedures. The characterization and quantification of venous valves could explain the difficulty or success in accessing targeted coronary venous locations.
|Number of pages
|Journal of Interventional Cardiac Electrophysiology
|Published - Nov 2008
Bibliographical noteFunding Information:
Acknowledgements The authors would like to sincerely thank LifeSource and the University of Minnesota Anatomy Bequest Program for their assistance with this study and the generous individuals and families who, by donating their hearts for research, made this study possible. We would also like to thank Gary Williams for his assistance with the figures and video compilation and Monica Mahre for her assistance with the preparation of this manuscript. This work was supported in part by the Institute for Engineering in Medicine at the University of Minnesota and by Medtronic.
- Coronary veins
- Left ventricle