Vasodilator Therapy of Myocardial Infarction

Research output: Contribution to journalEditorial

21 Citations (Scopus)

Abstract

Recent interest in pharmacologic interventions to alter the course of acute myocardial infarction has led to the consideration of arterial pressure and systemic vascular resistance as factors controlling left ventricular function. In the first 24 hours after the onset of symptoms, the circulatory pattern of extensive transmural acute myocardial infarction is characterized by increased left ventricular end-diastolic pressure, reduced stroke volume and normal or even elevated arterial pressure.1 Maintenance of the arterial pressure in the face of a reduction in cardiac output implies an increase in peripheral resistance that may, in part, represent the vascular consequence of activation of the.

Original languageEnglish (US)
Pages (from-to)1433-1434
Number of pages2
JournalNew England Journal of Medicine
Volume290
Issue number25
DOIs
StatePublished - Jun 20 1974

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Vasodilator Agents
Vascular Resistance
Arterial Pressure
Myocardial Infarction
R Factors
Left Ventricular Function
Cardiac Output
Stroke Volume
Blood Vessels
Maintenance
Blood Pressure
Therapeutics

Cite this

Vasodilator Therapy of Myocardial Infarction. / Cohn, Jay N.

In: New England Journal of Medicine, Vol. 290, No. 25, 20.06.1974, p. 1433-1434.

Research output: Contribution to journalEditorial

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