Vascular compliance in hypertension

Stanley M Finkelstein, William Feske, James Mock, Peter Carlyle, Thomas Rector, Spencer Kubo, Jay N Cohn

Research output: Contribution to conferencePaper

6 Citations (Scopus)

Abstract

Pulse contour analysis was used to determine systemic arterial vascular compliance in hypertensive (HT) and normotensive (NT) subjects. In seven hypertensives aged 43-58 yrs (mean age 52.1 ± 5.5 yrs) and seven normotensives aged 33-59 yrs (mean age 43.7 ± 9.9 yrs) both large artery (C1) and distal arterial (C2) compliance were determined from a peripheral arterial pressure waveform and cardiac output. Age differences were not statistically significant. Mean arterial pressure was 29% higher in HT (p < 0.001). Cardiac output was 12% higher and heart rate was 6% lower in HT, but these differences were not significant. Systemic vascular resistance was 17% higher in HT (NS), while proximal and distal arterial compliance were 15% and 70% lower, respectively, in HT compared to NT. Only the difference in C2 was significant (p < 0.02). Thus, distal vascular compliance may be a clinically useful parameter for evaluating hypertensive subjects before and during therapeutic intervention.

Original languageEnglish (US)
Pages241-242
Number of pages2
StatePublished - Nov 1 1988
EventProceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society - New Orleans, LA, USA
Duration: Nov 4 1988Nov 7 1988

Other

OtherProceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society
CityNew Orleans, LA, USA
Period11/4/8811/7/88

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Finkelstein, S. M., Feske, W., Mock, J., Carlyle, P., Rector, T., Kubo, S., & Cohn, J. N. (1988). Vascular compliance in hypertension. 241-242. Paper presented at Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, New Orleans, LA, USA, .

Vascular compliance in hypertension. / Finkelstein, Stanley M; Feske, William; Mock, James; Carlyle, Peter; Rector, Thomas; Kubo, Spencer; Cohn, Jay N.

1988. 241-242 Paper presented at Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, New Orleans, LA, USA, .

Research output: Contribution to conferencePaper

Finkelstein, SM, Feske, W, Mock, J, Carlyle, P, Rector, T, Kubo, S & Cohn, JN 1988, 'Vascular compliance in hypertension' Paper presented at Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, New Orleans, LA, USA, 11/4/88 - 11/7/88, pp. 241-242.
Finkelstein SM, Feske W, Mock J, Carlyle P, Rector T, Kubo S et al. Vascular compliance in hypertension. 1988. Paper presented at Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, New Orleans, LA, USA, .
Finkelstein, Stanley M ; Feske, William ; Mock, James ; Carlyle, Peter ; Rector, Thomas ; Kubo, Spencer ; Cohn, Jay N. / Vascular compliance in hypertension. Paper presented at Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, New Orleans, LA, USA, .2 p.
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AU - Feske, William

AU - Mock, James

AU - Carlyle, Peter

AU - Rector, Thomas

AU - Kubo, Spencer

AU - Cohn, Jay N

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N2 - Pulse contour analysis was used to determine systemic arterial vascular compliance in hypertensive (HT) and normotensive (NT) subjects. In seven hypertensives aged 43-58 yrs (mean age 52.1 ± 5.5 yrs) and seven normotensives aged 33-59 yrs (mean age 43.7 ± 9.9 yrs) both large artery (C1) and distal arterial (C2) compliance were determined from a peripheral arterial pressure waveform and cardiac output. Age differences were not statistically significant. Mean arterial pressure was 29% higher in HT (p < 0.001). Cardiac output was 12% higher and heart rate was 6% lower in HT, but these differences were not significant. Systemic vascular resistance was 17% higher in HT (NS), while proximal and distal arterial compliance were 15% and 70% lower, respectively, in HT compared to NT. Only the difference in C2 was significant (p < 0.02). Thus, distal vascular compliance may be a clinically useful parameter for evaluating hypertensive subjects before and during therapeutic intervention.

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