Validity of the Hamilton rating scale for depression

J. W. Knesevich, J. T. Biggs, P. J. Clayton, V. E. Ziegler

Research output: Contribution to journalArticlepeer-review

91 Scopus citations


In 26 depressed patients, a high correlation (0.89) was found between the Hamilton score and a psychiatrist's global rating and between the change (0.68) in these ratings during treatment. The Hamilton scale was able to differentiate at the 0.01 level four degrees of severity based on the global rating. Limiting the range of severity measured was found to lower significantly the correlation between the ratings. A prospective examination of a six-item sub-scale of the Hamilton scale developed by Beck and associates failed to confirm its claimed improvement in sensitivity or validity.

Original languageEnglish (US)
Pages (from-to)49-52
Number of pages4
JournalBritish Journal of Psychiatry
Issue number7
StatePublished - 1977


Dive into the research topics of 'Validity of the Hamilton rating scale for depression'. Together they form a unique fingerprint.

Cite this