Validation of the brief cognitive symptoms index in Sjögren syndrome

Barbara M. Segal, Nelson L Rhodus, Kathy L. Moser Sivils, Craig A. Solid

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Objective. The Brief Cognitive Symptoms Inventory (BCSI) is a short, self-report scale designed to measure cognitive symptomatology in patients with rheumatic disease. To facilitate research and clinical practice, we tested the internal consistency and validity of the BCSI in patients with Sjögren syndrome (SS). Methods. Patients who met the American-European Consensus Group criteria for SS and healthy controls completed a questionnaire assessing symptoms including cognitive complaints. We calculated Cronbach's alpha to assess internal consistency and Pearson correlation coefficients to test for association between BCSI, symptoms, and demographic variables. Total score distribution was analyzed to establish cutoff criteria for differentiation of case versus non-case. We compared neuropsychological outcomes of patients with SS above and below the threshold BCSI score to assess the association of cognitive symptoms with objective cognitive deficits. Results. Complete data were available on 144 patients with SS and 35 controls. Internal consistency of the BCSI was good. Scores were similar in all patient groups and patients reported more cognitive symptoms than controls (p < 0.0001). BCSI scores correlated moderately with pain, depression, anxiety, fatigue, and health quality. High scores for cognitive dysfunction were reported by 20% of the patients with SS and only 3% of controls. Patients with cognitive scores > 50 had more depression, fatigue, pain (effect size all > 1), and worse performance on multiple cognitive domains. Conclusion. The BCSI should be a useful tool for the study of cognitive symptoms in SS. Both self-report and standardized tests should be considered in screening for cognitive disorders in SS.

Original languageEnglish (US)
Pages (from-to)2027-2033
Number of pages7
JournalJournal of Rheumatology
Volume41
Issue number10
DOIs
StatePublished - Oct 1 2014

Fingerprint

Neurobehavioral Manifestations
Equipment and Supplies
Self Report
Rheumatic Diseases
Fatigue
Consensus
Demography
Depression
Pain

Keywords

  • Neurobehavioral manifestations
  • Self-report
  • Sjögren syndrome

Cite this

Validation of the brief cognitive symptoms index in Sjögren syndrome. / Segal, Barbara M.; Rhodus, Nelson L; Moser Sivils, Kathy L.; Solid, Craig A.

In: Journal of Rheumatology, Vol. 41, No. 10, 01.10.2014, p. 2027-2033.

Research output: Contribution to journalArticle

Segal, Barbara M. ; Rhodus, Nelson L ; Moser Sivils, Kathy L. ; Solid, Craig A. / Validation of the brief cognitive symptoms index in Sjögren syndrome. In: Journal of Rheumatology. 2014 ; Vol. 41, No. 10. pp. 2027-2033.
@article{478e365759e44b809413e823c66d3ed7,
title = "Validation of the brief cognitive symptoms index in Sj{\"o}gren syndrome",
abstract = "Objective. The Brief Cognitive Symptoms Inventory (BCSI) is a short, self-report scale designed to measure cognitive symptomatology in patients with rheumatic disease. To facilitate research and clinical practice, we tested the internal consistency and validity of the BCSI in patients with Sj{\"o}gren syndrome (SS). Methods. Patients who met the American-European Consensus Group criteria for SS and healthy controls completed a questionnaire assessing symptoms including cognitive complaints. We calculated Cronbach's alpha to assess internal consistency and Pearson correlation coefficients to test for association between BCSI, symptoms, and demographic variables. Total score distribution was analyzed to establish cutoff criteria for differentiation of case versus non-case. We compared neuropsychological outcomes of patients with SS above and below the threshold BCSI score to assess the association of cognitive symptoms with objective cognitive deficits. Results. Complete data were available on 144 patients with SS and 35 controls. Internal consistency of the BCSI was good. Scores were similar in all patient groups and patients reported more cognitive symptoms than controls (p < 0.0001). BCSI scores correlated moderately with pain, depression, anxiety, fatigue, and health quality. High scores for cognitive dysfunction were reported by 20{\%} of the patients with SS and only 3{\%} of controls. Patients with cognitive scores > 50 had more depression, fatigue, pain (effect size all > 1), and worse performance on multiple cognitive domains. Conclusion. The BCSI should be a useful tool for the study of cognitive symptoms in SS. Both self-report and standardized tests should be considered in screening for cognitive disorders in SS.",
keywords = "Neurobehavioral manifestations, Self-report, Sj{\"o}gren syndrome",
author = "Segal, {Barbara M.} and Rhodus, {Nelson L} and {Moser Sivils}, {Kathy L.} and Solid, {Craig A.}",
year = "2014",
month = "10",
day = "1",
doi = "10.3899/jrheum.140362",
language = "English (US)",
volume = "41",
pages = "2027--2033",
journal = "Journal of Rheumatology",
issn = "0315-162X",
publisher = "Journal of Rheumatology",
number = "10",

}

TY - JOUR

T1 - Validation of the brief cognitive symptoms index in Sjögren syndrome

AU - Segal, Barbara M.

AU - Rhodus, Nelson L

AU - Moser Sivils, Kathy L.

AU - Solid, Craig A.

PY - 2014/10/1

Y1 - 2014/10/1

N2 - Objective. The Brief Cognitive Symptoms Inventory (BCSI) is a short, self-report scale designed to measure cognitive symptomatology in patients with rheumatic disease. To facilitate research and clinical practice, we tested the internal consistency and validity of the BCSI in patients with Sjögren syndrome (SS). Methods. Patients who met the American-European Consensus Group criteria for SS and healthy controls completed a questionnaire assessing symptoms including cognitive complaints. We calculated Cronbach's alpha to assess internal consistency and Pearson correlation coefficients to test for association between BCSI, symptoms, and demographic variables. Total score distribution was analyzed to establish cutoff criteria for differentiation of case versus non-case. We compared neuropsychological outcomes of patients with SS above and below the threshold BCSI score to assess the association of cognitive symptoms with objective cognitive deficits. Results. Complete data were available on 144 patients with SS and 35 controls. Internal consistency of the BCSI was good. Scores were similar in all patient groups and patients reported more cognitive symptoms than controls (p < 0.0001). BCSI scores correlated moderately with pain, depression, anxiety, fatigue, and health quality. High scores for cognitive dysfunction were reported by 20% of the patients with SS and only 3% of controls. Patients with cognitive scores > 50 had more depression, fatigue, pain (effect size all > 1), and worse performance on multiple cognitive domains. Conclusion. The BCSI should be a useful tool for the study of cognitive symptoms in SS. Both self-report and standardized tests should be considered in screening for cognitive disorders in SS.

AB - Objective. The Brief Cognitive Symptoms Inventory (BCSI) is a short, self-report scale designed to measure cognitive symptomatology in patients with rheumatic disease. To facilitate research and clinical practice, we tested the internal consistency and validity of the BCSI in patients with Sjögren syndrome (SS). Methods. Patients who met the American-European Consensus Group criteria for SS and healthy controls completed a questionnaire assessing symptoms including cognitive complaints. We calculated Cronbach's alpha to assess internal consistency and Pearson correlation coefficients to test for association between BCSI, symptoms, and demographic variables. Total score distribution was analyzed to establish cutoff criteria for differentiation of case versus non-case. We compared neuropsychological outcomes of patients with SS above and below the threshold BCSI score to assess the association of cognitive symptoms with objective cognitive deficits. Results. Complete data were available on 144 patients with SS and 35 controls. Internal consistency of the BCSI was good. Scores were similar in all patient groups and patients reported more cognitive symptoms than controls (p < 0.0001). BCSI scores correlated moderately with pain, depression, anxiety, fatigue, and health quality. High scores for cognitive dysfunction were reported by 20% of the patients with SS and only 3% of controls. Patients with cognitive scores > 50 had more depression, fatigue, pain (effect size all > 1), and worse performance on multiple cognitive domains. Conclusion. The BCSI should be a useful tool for the study of cognitive symptoms in SS. Both self-report and standardized tests should be considered in screening for cognitive disorders in SS.

KW - Neurobehavioral manifestations

KW - Self-report

KW - Sjögren syndrome

UR - http://www.scopus.com/inward/record.url?scp=84973424376&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84973424376&partnerID=8YFLogxK

U2 - 10.3899/jrheum.140362

DO - 10.3899/jrheum.140362

M3 - Article

VL - 41

SP - 2027

EP - 2033

JO - Journal of Rheumatology

JF - Journal of Rheumatology

SN - 0315-162X

IS - 10

ER -