Validation of a point-of-care rapid diagnostic test for hepatitis C for use in resource-limited settings

James S. Leathers, Maria Belen Pisano, Viviana Re, Gertine van Oord, Amir Sultan, Andre Boonstra, Jose D. Debes

Research output: Contribution to journalArticle

Abstract

BACKGROUND: Treatment of HCV with direct-acting antivirals has enabled the discussion of HCV eradication worldwide. Envisioning this aim requires implementation of mass screening in resource-limited areas, usually constrained by testing costs. METHODS: We validated a low-cost, rapid diagnosis test (RDT) for HCV in three different continents in 141 individuals. RESULTS: The HCV RDT showed 100% specificity and sensitivity across different samples regardless of genotype or viral load (in samples with such information, 90%). CONCLUSIONS: The HCV test validated in this study can allow for HCV screening in areas of need when properly used.

Original languageEnglish (US)
Pages (from-to)314-315
Number of pages2
JournalInternational health
Volume11
Issue number4
DOIs
StatePublished - Jul 1 2019

Keywords

  • hepatitis C
  • rapid diagnostic test
  • resource-limited

PubMed: MeSH publication types

  • Journal Article
  • Research Support, Non-U.S. Gov't
  • Validation Study

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