TY - JOUR
T1 - Validating an Ataxia Functional Composite Scale in spinocerebellar ataxia
AU - Assadi, Mitra
AU - Leone, Paola
AU - Veloski, J. Jon
AU - Schwartzman, Robert J.
AU - Janson, Christopher G.
AU - Campellone, Joseph V.
PY - 2008/5/15
Y1 - 2008/5/15
N2 - The Ataxia Functional Composite Scale (AFCS) may provide a sensitive and reproducible assessment of treatment responses in studies of the spinocerebellar ataxias (SCA). We previously assessed the effects of buspirone in a cohort of patients with SCA via the International Cooperative Ataxia Rating Scale (ICARS). At each assessment period, AFCS scores were also obtained. A strong correlation of AFCS with ICARS scores was demonstrated at all assessment periods. This study supports the validity of the AFCS as a useful assessment of ataxia in this population.
AB - The Ataxia Functional Composite Scale (AFCS) may provide a sensitive and reproducible assessment of treatment responses in studies of the spinocerebellar ataxias (SCA). We previously assessed the effects of buspirone in a cohort of patients with SCA via the International Cooperative Ataxia Rating Scale (ICARS). At each assessment period, AFCS scores were also obtained. A strong correlation of AFCS with ICARS scores was demonstrated at all assessment periods. This study supports the validity of the AFCS as a useful assessment of ataxia in this population.
KW - Ataxia
KW - Clinical assessment
KW - SCA
UR - http://www.scopus.com/inward/record.url?scp=40849119870&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=40849119870&partnerID=8YFLogxK
U2 - 10.1016/j.jns.2007.11.016
DO - 10.1016/j.jns.2007.11.016
M3 - Article
C2 - 18191149
AN - SCOPUS:40849119870
SN - 0022-510X
VL - 268
SP - 136
EP - 139
JO - Journal of the Neurological Sciences
JF - Journal of the Neurological Sciences
IS - 1-2
ER -