Validating an Ataxia Functional Composite Scale in spinocerebellar ataxia

Mitra Assadi, Paola Leone, J. Jon Veloski, Robert J. Schwartzman, Christopher G. Janson, Joseph V. Campellone

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


The Ataxia Functional Composite Scale (AFCS) may provide a sensitive and reproducible assessment of treatment responses in studies of the spinocerebellar ataxias (SCA). We previously assessed the effects of buspirone in a cohort of patients with SCA via the International Cooperative Ataxia Rating Scale (ICARS). At each assessment period, AFCS scores were also obtained. A strong correlation of AFCS with ICARS scores was demonstrated at all assessment periods. This study supports the validity of the AFCS as a useful assessment of ataxia in this population.

Original languageEnglish (US)
Pages (from-to)136-139
Number of pages4
JournalJournal of the Neurological Sciences
Issue number1-2
StatePublished - May 15 2008
Externally publishedYes


  • Ataxia
  • Clinical assessment
  • SCA


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