Validating an Ataxia Functional Composite Scale in spinocerebellar ataxia

Mitra Assadi; Paola Leone; J. Jon Veloski; Robert J. Schwartzman; Christopher G. Janson; Joseph V. Campellone

doi:10.1016/j.jns.2007.11.016

Validating an Ataxia Functional Composite Scale in spinocerebellar ataxia

Mitra Assadi, Paola Leone, J. Jon Veloski, Robert J. Schwartzman, Christopher G. Janson, Joseph V. Campellone

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

The Ataxia Functional Composite Scale (AFCS) may provide a sensitive and reproducible assessment of treatment responses in studies of the spinocerebellar ataxias (SCA). We previously assessed the effects of buspirone in a cohort of patients with SCA via the International Cooperative Ataxia Rating Scale (ICARS). At each assessment period, AFCS scores were also obtained. A strong correlation of AFCS with ICARS scores was demonstrated at all assessment periods. This study supports the validity of the AFCS as a useful assessment of ataxia in this population.

Original language	English (US)
Pages (from-to)	136-139
Number of pages	4
Journal	Journal of the Neurological Sciences
Volume	268
Issue number	1-2
DOIs	https://doi.org/10.1016/j.jns.2007.11.016
State	Published - May 15 2008
Externally published	Yes

Keywords

Ataxia
Clinical assessment
SCA

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10.1016/j.jns.2007.11.016

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abstract = "The Ataxia Functional Composite Scale (AFCS) may provide a sensitive and reproducible assessment of treatment responses in studies of the spinocerebellar ataxias (SCA). We previously assessed the effects of buspirone in a cohort of patients with SCA via the International Cooperative Ataxia Rating Scale (ICARS). At each assessment period, AFCS scores were also obtained. A strong correlation of AFCS with ICARS scores was demonstrated at all assessment periods. This study supports the validity of the AFCS as a useful assessment of ataxia in this population.",

keywords = "Ataxia, Clinical assessment, SCA",

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AU - Assadi, Mitra

AU - Leone, Paola

AU - Veloski, J. Jon

AU - Schwartzman, Robert J.

AU - Janson, Christopher G.

AU - Campellone, Joseph V.

PY - 2008/5/15

Y1 - 2008/5/15

N2 - The Ataxia Functional Composite Scale (AFCS) may provide a sensitive and reproducible assessment of treatment responses in studies of the spinocerebellar ataxias (SCA). We previously assessed the effects of buspirone in a cohort of patients with SCA via the International Cooperative Ataxia Rating Scale (ICARS). At each assessment period, AFCS scores were also obtained. A strong correlation of AFCS with ICARS scores was demonstrated at all assessment periods. This study supports the validity of the AFCS as a useful assessment of ataxia in this population.

AB - The Ataxia Functional Composite Scale (AFCS) may provide a sensitive and reproducible assessment of treatment responses in studies of the spinocerebellar ataxias (SCA). We previously assessed the effects of buspirone in a cohort of patients with SCA via the International Cooperative Ataxia Rating Scale (ICARS). At each assessment period, AFCS scores were also obtained. A strong correlation of AFCS with ICARS scores was demonstrated at all assessment periods. This study supports the validity of the AFCS as a useful assessment of ataxia in this population.

KW - Ataxia

KW - Clinical assessment

KW - SCA

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JF - Journal of the Neurological Sciences

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ER -

Validating an Ataxia Functional Composite Scale in spinocerebellar ataxia

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