Utility of Functional Pneumonectomy by Using Intrabronchial Valves

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


Background: Intrabronchial valves are approved for bronchoscopic lung volume reduction in chronic obstructive pulmonary disease patients and used for prolonged air leak. There is no data on bronchoscopic functional pneumonectomy (BFP) when treating patients with persistent air leak (PAL) or for lung volume reduction purposes. Methods: In this observational study, 10 consecutive patients who failed to improve with traditional therapies were assessed after they underwent BFP for PAL or lung volume reduction. Results: Ten patients underwent 17 valve placement procedures; 82 valves were placed (median: 8; range: 5 to 12). BFP was performed in 1 single lung transplant patient with hyperinflation of native lung compromising lung function. The rest of the patients had prolonged air leak because of various reasons; spontaneous (n = 7) and postoperative (n = 2). Pneumonia was the only procedure-related complication seen in 1 patient. Of patients with prolonged air leak with chest tubes (n = 9), all had successful chest tube removal (median of 7 days; range: 3 to 21 d). The valves were removed within 6 weeks of chest tube removal in 6 patients. Prebronchoscopic and post-BFP actual forced expiratory volume in first second values in 2 transplant patients. Conclusion: PAL usually occurs in patients with severe underlying lung condition or after surgery. Management of PAL can be challenging despite pleurodesis (medical or surgical). BFP offers a minimally invasive management option.

Original languageEnglish (US)
JournalJournal of Bronchology and Interventional Pulmonology
StateAccepted/In press - 2021

Bibliographical note

Publisher Copyright:
Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.


  • Intrabronchial valves
  • Lung volume reduction
  • Pneumonectomy
  • Prolonged air leak

PubMed: MeSH publication types

  • Journal Article
  • Observational Study


Dive into the research topics of 'Utility of Functional Pneumonectomy by Using Intrabronchial Valves'. Together they form a unique fingerprint.

Cite this