@inbook{12b3a2bbaa304c8ebb2166b32a166e28,
title = "Using Oct4:MerCreMer lineage tracing to monitor endogenous Oct4 expression during the reprogramming of fibroblasts into induced pluripotent stem cells (iPSCs)",
abstract = "The reprogramming of somatic cells into induced pluripotent stem cells (iPSCs) using a combination of defined transcription factors has become one of the most widely used techniques in stem cell biology. A critical, early event in iPSC reprogramming is the induction of the endogenous transcription factor network that maintains pluripotency in iPSCs. Here we describe using a transgenic, conditional Oct4-Cre construct to investigate the spatial and temporal induction of endogenous Oct4 expression during the reprogramming of mouse fibroblasts into iPS cells.",
keywords = "IPSC, Induced pluripotent stem cell, Lineage tracing, Oct4, Oct4-Cre, Reprogramming",
author = "Greder, {Lucas V.} and Jason Post and Dutton, {James R.}",
year = "2016",
month = jan,
day = "1",
doi = "10.1007/7651_2015_198",
language = "English (US)",
series = "Methods in Molecular Biology",
publisher = "Humana Press Inc.",
pages = "97--110",
booktitle = "Methods in Molecular Biology",
}