Clinical practice guidelines (CPGs) were originally designed to help with evidence-based management of a single disease and such single disease focus has impacted research on CPG computerization. This computerization is mostly concerned with supporting different representation formats and identifying potential inconsistencies in the definitions of CPGs. However, one of the biggest challenges facing physicians is the application of multiple CPGs to comorbid patients. While various research initiatives propose ways of mitigating adverse interactions in concurrently applied CPGs, there are no attempts to develop a generalized framework for mitigation that captures generic characteristics of the problem, while handling nuances such as precedence relationships. In this paper we present our research towards developing a mitigation framework that relies on a first-order logic-based representation and related theorem proving and model finding techniques. The application of the proposed framework is illustrated with a simple clinical example.
|Original language||English (US)|
|Title of host publication||Knowledge Representation for Health Care - 6th International Workshop, KR4HC 2014, Revised Selected Papers|
|Subtitle of host publication||Making Personalized and Participatory Medicine a Reality - Papers from the AAAI Fall Symposium, Technical Report|
|Editors||Annette ten Teije, Silvia Miksch, David Riaño|
|Number of pages||17|
|State||Published - Jan 1 2014|
|Event||6th International Workshop on Knowledge Representation for Heath Care, KR4HC 2014 held as part of the 14th International Conference on Principles of Knowledge Representation and Reasoning, VSL 2014 - Vienna, Austria|
Duration: Jul 21 2014 → Jul 21 2014
|Name||Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)|
|Other||6th International Workshop on Knowledge Representation for Heath Care, KR4HC 2014 held as part of the 14th International Conference on Principles of Knowledge Representation and Reasoning, VSL 2014|
|Period||7/21/14 → 7/21/14|
Bibliographical notePublisher Copyright:
© Springer International Publishing Switzerland 2014.