Using addiction severity profiles to differentiate cocaine-dependent patients with and without comorbid major depression

Adam M. Leventhal, Marc E. Mooney, Katherine A. DeLaune, Joy M. Schmitz

Research output: Contribution to journalArticlepeer-review

17 Scopus citations

Abstract

This study compared pretreatment addiction severity profiles of 339 abusers in three diagnostic groups: cocaine dependence only (CO), cocaine dependence with substance-induced major depression (SIMD), and cocaine dependence with independent major depression (IMD). Depressed subjects reported more severe problems than non-depressed subjects across numerous domains, regardless of diagnostic etiology. These findings support the need for specialized treatment approaches targeting depressive symptoms or life stress for cocaine-dependent patients with IMD or SIMD, though patients with IMD may require additional attention for chronic and comorbid psychiatric and medical problems.

Original languageEnglish (US)
Pages (from-to)362-369
Number of pages8
JournalAmerican Journal on Addictions
Volume15
Issue number5
DOIs
StatePublished - Oct 1 2006

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