Usefulness of twin studies for exploring the etiology of childhood and adolescent psychiatric disorders

M. C. LaBuda, I. I. Gottesman, D. L. Pauls

Research output: Contribution to journalArticle

30 Scopus citations

Abstract

It is estimated that approximately 12% of the individuals under the age of 18 in the United States have a diagnosable mental illness [Institute of Medicine, 1989]; however, only a minority of the etiological research in psychopathology focuses on disorders with childhood onset. The present report demonstrates the usefulness of twin studies in exploring the etiology of childhood and adolescent psychiatric psychopathology and reviews the design, methodology, and results from traditional twin studies of various behavioral disorders. Alternative twin designs are also reviewed in an effort to address the future direction of twin studies in the area of childhood and adolescent psychopathology and to illustrate that twin data have much more to offer the field of psychopathology than merely an initial test to rule in or to rule out a significant genetic contribution to the development of such behaviors.

Original languageEnglish (US)
Pages (from-to)47-59
Number of pages13
JournalAmerican Journal of Medical Genetics
Volume48
Issue number1
DOIs
StatePublished - Jan 1 1993

Keywords

  • childhood psychopathology
  • genetics
  • twins

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