Use of the electrical aerosol detector as an indicator of the surface area of fine particles deposited in the lung

William E. Wilson, John Stanek, Han Hee-Siew (Ryan), Tim Johnson, Hiromu Sakurai, David Y.H. Pui, Jay Turner, Da Ren Chen, Scott Duthie

Research output: Contribution to journalArticlepeer-review

42 Scopus citations

Abstract

Because of recent concerns about the health effects of ultrafine particles and the indication that particle toxicity is related to surface area, we have been examining techniques for measuring parameters related to the surface area of fine particles, especially in the 0.003- to 0.5-µm size range. In an earlier study, we suggested that the charge attached to particles, as measured by a prototype of the Electrical Aerosol Detector (EAD, TSI Inc., Model 3070), was related to the 1.16 power of the mobility diameter. An inspection of the pattern of particle deposition in the lung as a function of particle size suggested that the EAD measurement might be a useful indicator of the surface area of particles deposited in the lung. In this study, we calculate the particle surface area (micrometer squared) deposited in the lung per cubic centimeter of air inhaled as a function of particle size using atmospheric particle size distributions measured in Minneapolis, MN, and East St. Louis, IL. The correlations of powers of the mobility diameter, D.

Original languageEnglish (US)
Pages (from-to)211-220
Number of pages10
JournalJournal of the Air and Waste Management Association
Volume57
Issue number2
DOIs
StatePublished - Feb 2007

Bibliographical note

Funding Information:
U.S. Environmental Protection Agency (EPA), through its Office of Research and Development, partially funded the research described here under Contract 3C-R003-NAEX to the University of Minnesota. The East St. Louis field measurements were supported by EPA (as part of the agency’s Supersite Program) under agreement R-82805901 X-13 98722301 to Washington University. This paper has been subjected to EPA review and approved for publication. However, the views expressed are those of the authors and do not necessarily reflect the views or policies of EPA. Mention of trade names or commercial products does not constitute endorsement or recommendation for use.

Fingerprint Dive into the research topics of 'Use of the electrical aerosol detector as an indicator of the surface area of fine particles deposited in the lung'. Together they form a unique fingerprint.

Cite this