Use of surrogate information time for monitoring the effect of treatment on the change in a response variable in clinical trials

Keyphrases

• Clinical Trial Data 50%
• Clinical Trials 100%
• Function Approach 50%
• Health Studies 50%
• Information Time 100%
• Interim Analysis 50%
• Lung Health 50%
• Rate of Change 50%
• Repeated Measurements 50%
• Response Variable 100%
• Situation of Uncertainty 50%
• Spending Function 50%
• Surrogate Data 100%
• Treatment Effect 100%
• Variance Parameter 50%

Mathematics

• Change Rate 50%
• Interim Analysis 50%
• Repeated Measurement 50%
• Response Variable 100%
• Variance 100%