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Use of Skin Biopsy in the Diagnosis of Small Fibre Neuropathy

  • G. Lauria
  • , S. T. Hsieh
  • , O. Johansson
  • , W. R. Kennedy
  • , J. M. Leger
  • , S. I. Mellgren
  • , M. Nolano
  • , I. S.J. Merkies
  • , M. Polydefkis
  • , A. G. Smith
  • , C. Sommer
  • , J. Valls-Solé

Research output: Chapter in Book/Report/Conference proceedingChapter

Original languageEnglish (US)
Title of host publicationEuropean Handbook of Neurological Management
Subtitle of host publicationSecond Edition
PublisherWiley-Blackwell
Pages81-90
Number of pages10
Volume1
ISBN (Print)9781405185332
DOIs
StatePublished - Sep 6 2010

Keywords

  • Clinical applications of skin biopsy in SFN-using similar inclusion criteria for patients
  • Correlation with small fibre-related evoked potentials
  • Data extraction, carried out-and compared among each member of task force
  • Document, written under auspices of European Federation of the Neurological Societies (EFNS)
  • IENF morphometry and measurement reliability
  • Less invasive sampling method-removal of epidermis alone by applying a suction capsule to skin
  • Normative reference values-Bright-field immunohistochemistry
  • Perform skin biopsy and choice of biopsy location
  • Quantification of sweat gland innervation
  • Skin biopsy use-in diagnosis of small fibre neuropathy

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