Use of magnetic resonance spectroscopy for in vivo evaluation of high- energy phosphate metabolism in normal and abnormal myocardium

Jianyi Zhang, Kamil Ugurbil, Arthur H.L. From, Robert J. Bache

Research output: Contribution to journalArticlepeer-review

13 Scopus citations

Abstract

31P- and 1H-nuclear magnetic resonance spectroscopy (MRS) are powerful tools for studying myocardial energy metabolism. The purpose of this review is to illustrate how these MRS techniques can be used to study complex bioenergetic issues in normal and abnormal in vivo myocardium. The results provide insight into the energetic alterations present in remodeled and hypertrophied myocardium. A detailed understanding of energy metabolism in normal and abnormal myocardium may point the way to improved preventive, diagnostic, and therapeutic modalities for left ventricular dysfunction.

Original languageEnglish (US)
Pages (from-to)23-32
Number of pages10
JournalJournal of Cardiovascular Magnetic Resonance
Volume2
Issue number1
DOIs
StatePublished - 2000

Keywords

  • Deoxymyoglobin
  • High-energy phosphates
  • Left ventricular hypertrophy
  • Left ventricular remodeling
  • Myocardial ischemia

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