Use of Lactate in Small Animal Clinical Practice

Leslie C. Sharkey, Maxey L. Wellman

Research output: Contribution to journalReview articlepeer-review

5 Scopus citations


Lactate is a product of anaerobic metabolism. Lactate concentration in blood is used clinically as an indicator of tissue hypoperfusion and hypoxia to determine disease severity, assess response to therapy, and predict outcome. This article reviews lactate physiology, sample collection and processing, and interpretation of lactate concentration in clinical practice.

Original languageEnglish (US)
Pages (from-to)567-577
Number of pages11
JournalClinics in Laboratory Medicine
Issue number3
StatePublished - Sep 1 2015

Bibliographical note

Publisher Copyright:
© 2015 Elsevier Inc.


  • D-Lactate
  • Hypoperfusion
  • Hypoxia
  • L-Lactate
  • Lactate
  • Lactic acidosis
  • Metabolic acidosis


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