Use of DNA probes from the 5′ flanking region of the HLA-B gene to examine polymorphism at the HLA-B locus

Karyn Steere, Beth Sidwell, Robin Leach, Francis E. Ward, Joel D. Taurog, Harry T. Orr

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Two DNA probes isolated from the region 5′ to the HLA-B gene are described. One of these, pCH6, detects a TaqI polymorphism which is correlated with serological alleles of HLA-B. Both probes are used to show a high level of DNA sequence homology between the 5′ flanking region of HLA-B and HLA-C.

Original languageEnglish (US)
Pages (from-to)137-147
Number of pages11
JournalHuman Immunology
Volume16
Issue number2
DOIs
StatePublished - Jun 1986

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HLA-B Antigens
5' Flanking Region
DNA Probes
HLA-C Antigens
Genes
Sequence Homology
Alleles

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Use of DNA probes from the 5′ flanking region of the HLA-B gene to examine polymorphism at the HLA-B locus. / Steere, Karyn; Sidwell, Beth; Leach, Robin; Ward, Francis E.; Taurog, Joel D.; Orr, Harry T.

In: Human Immunology, Vol. 16, No. 2, 06.1986, p. 137-147.

Research output: Contribution to journalArticle

Steere, Karyn ; Sidwell, Beth ; Leach, Robin ; Ward, Francis E. ; Taurog, Joel D. ; Orr, Harry T. / Use of DNA probes from the 5′ flanking region of the HLA-B gene to examine polymorphism at the HLA-B locus. In: Human Immunology. 1986 ; Vol. 16, No. 2. pp. 137-147.
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