Use of complementary medicine by adult patients participating in HIV/AIDS clinical trials

A. Sparber, J. C. Wootton, L. Bauer, G. Curt, David M Eisenberg, T. Levin, S. M. Steinberg

Research output: Contribution to journalArticle

72 Citations (Scopus)

Abstract

Objective: To identify and characterize patterns of use of complementary and alternative (CAM) therapies by human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) patients participating in clinical trials in a research setting. Design: A descriptive survey using a nonrandom sample of 100 patients was conducted over 17 months, using a 99-item interview schedule adapted from a previous study. Setting: National Institutes of Health (NIH) Warren G. Magnuson Clinical Center. Subjects: Patients diagnosed with HIV/AIDS, participating in clinical research protocols at the National Institute of Allergy and Infectious Diseases and the National Cancer institute (NCI) at the NIH. Results: Ninety-one percent (91%) had used at least one CAM therapy, as defined by a 1993 study by Eisenberg et al., sometime in their lives. Postdiagnosis, 84% used at least one CAM therapy with an average of just fewer than 5. The increase in frequency of use from 64% prediagnosis was significant (p2 = 0.019). Therapies that became significantly more popular postdiagnosis were, imagery (p2 = 0.00012), high-dose vitamins, (p2 = 0.000019), weight gain (p2 = 0.000244), massage (p2 = 0.00091), relaxation (p2 = 0.0033), herbals (p2 = 0.013), spiritual (p2 = 0.024), and acupuncture (p2 = 0.035). They were primarily used for HIV/AIDS-related problems: dermatological, nausea, depression, insomnia, and weakness. There was a high level of agreement that benefits of CAM use were: feeling better, 51 (98.1%), increased coping, 52 (100%), feeling in control, 44 (88.5%), and enhanced treatment outcome, 49 (94.2%) with 32 (61%) stating CAM was as, or more effective than conventional treatment. Fifty-three percent (53%) were specifically asked by physicians whether they were using adjunct therapies. Conclusions: Subjects used a variety of CAM therapies to cope with their diseases and rigors of treatment and clinical trials. Further research is needed to identify CAM therapies that may be used as adjunct treatments during clinical trials.

Original languageEnglish (US)
Pages (from-to)415-422
Number of pages8
JournalJournal of Alternative and Complementary Medicine
Volume6
Issue number5
DOIs
StatePublished - Jan 1 2000

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Complementary Therapies
Acquired Immunodeficiency Syndrome
Clinical Trials
HIV
Therapeutics
National Institutes of Health (U.S.)
Emotions
National Institute of Allergy and Infectious Diseases (U.S.)
Massage
National Cancer Institute (U.S.)
Imagery (Psychotherapy)
Sleep Initiation and Maintenance Disorders
Acupuncture
Clinical Protocols
Research
Vitamins
Nausea
Weight Gain
Appointments and Schedules
Interviews

Cite this

Sparber, A., Wootton, J. C., Bauer, L., Curt, G., Eisenberg, D. M., Levin, T., & Steinberg, S. M. (2000). Use of complementary medicine by adult patients participating in HIV/AIDS clinical trials. Journal of Alternative and Complementary Medicine, 6(5), 415-422. https://doi.org/10.1089/acm.2000.6.415

Use of complementary medicine by adult patients participating in HIV/AIDS clinical trials. / Sparber, A.; Wootton, J. C.; Bauer, L.; Curt, G.; Eisenberg, David M; Levin, T.; Steinberg, S. M.

In: Journal of Alternative and Complementary Medicine, Vol. 6, No. 5, 01.01.2000, p. 415-422.

Research output: Contribution to journalArticle

Sparber, A, Wootton, JC, Bauer, L, Curt, G, Eisenberg, DM, Levin, T & Steinberg, SM 2000, 'Use of complementary medicine by adult patients participating in HIV/AIDS clinical trials', Journal of Alternative and Complementary Medicine, vol. 6, no. 5, pp. 415-422. https://doi.org/10.1089/acm.2000.6.415
Sparber, A. ; Wootton, J. C. ; Bauer, L. ; Curt, G. ; Eisenberg, David M ; Levin, T. ; Steinberg, S. M. / Use of complementary medicine by adult patients participating in HIV/AIDS clinical trials. In: Journal of Alternative and Complementary Medicine. 2000 ; Vol. 6, No. 5. pp. 415-422.
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