Urinary MHPG and ward behavior in unmedicated psychiatric patients

Kim T. Mueser, Alexander J. Rosen, Maurice W. Dysken, Javaid I. Javaid

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


The relationship between urinary excretion of 3-methoxy-4-hydroxyphenylglycol (MHPG) and overt behaviors emitted in two hospital environments was examined in a group of 27 drug-free psychiatric patients. Depressed patients with high MHPG excretion ate less and engaged in less visual activity in the lunch environment. Schizophrenic patients but not depressive patients with high MHPG tended to have greater body activity during the gym environment. The implications of these findings for the identification of subtypes of depression and schizophrenia, and for an improved methodology in investigation of biobehavioral relations in clinical populations, are discussed.

Original languageEnglish (US)
Pages (from-to)275-283
Number of pages9
JournalPsychiatry Research
Issue number4
StatePublished - Dec 1983

Bibliographical note

Funding Information:
Acknowledgment. The authors express their thanks to the staffs on the ISPI researchw ards of 5 West and 9 East, and to Steve Sussman for his help in data collection. The researchr eported was supported in part by State of Illinois Department of Mental Health and Developmental Disabilities grants (nos. RD 83613a nd RD 62202).


  • MHPG
  • behavior
  • depression
  • naturalistic observations
  • psychopathology
  • schizophrenia


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