Urinary arsenic species are detectable in urban underserved hispanic/latino populations: A pilot study from the study of latinos: Nutrition & physical activity assessment study (SOLNAS)

H. Dean Hosgood, Vesna Slavkovich, Simin Hua, Madelyn Klugman, Maria Grau-Perez, Bharat Thyagarajan, Joseph Graziano, Jianwen Cai, Pamela A. Shaw, Robert Kaplan, Ana Navas-Acien, Yasmin Mossavar-Rahmani

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


Background: Hispanics/Latinos represent >15% of the United States (US) population and experience a high burden of cardiovascular disease (CVD) and diabetes. Dietary exposure, particularly to arsenic (As), may be associated with CVD and diabetes in Hispanics/Latinos. Rural populations in the US exposed to As in drinking water have increased risk of diabetes and CVD; however, little is known about the risk among urban populations with low As in water who are mostly exposed to As through food. Methods: To explore the levels of inorganic arsenic exposure (the sum of inorganic and methylated arsenic species in urine, ∑As, corrected by a residual-based method) in persons of Hispanic/Latino origin, we conducted a pilot study quantifying urinary arsenic levels among 45 participants in the Study of Latinos: Nutrition & Physical Activity Assessment Study (SOLNAS). Results: The median (interquartile range) of the urinary arsenic species (µg/L) were as follows: inorganic As 0.6 (0.4, 1.0), monomethylarsonic acid 1.2 (0.7, 1.9), dimethylarsinic acid 7.2 (4.3, 15.3), and ∑As 6.0 (4.3, 10.5). Conclusions: This study adds to the existing evidence that harmful forms of arsenic are present in this group of Hispanics/Latinos.

Original languageEnglish (US)
Article number2247
JournalInternational journal of environmental research and public health
Issue number7
StatePublished - Mar 27 2020

Bibliographical note

Funding Information:
The authors thank the staff and participants of HCHS/SOL for their important contributions. A complete list of staff and investigators has been provided by Sorlie P., et al. in Ann. Epidemiol. (2010) Aug; 20: 642?649 and is also available on the study website http://www.cscc.unc.edu/hchs/. This work was supported by R01HL095856, R01ES028758, P42ES010349, and P30ES009089. The Hispanic Community Health Study/Study of Latinos was carried out as a collaborative study supported by contracts from the National Heart, Lung, and Blood Institute (NHLBI) to the University of North Carolina (N01-HC65233), University of Miami (N01-HC65234), Albert Einstein College of Medicine (N01-HC65235), Northwestern University (N01-HC65236), and San Diego State University (N01-HC65237). The following Institutes/Centers/Offices contribute to the HCHS/SOL through a transfer of funds to the NHLBI: National Center on Minority Health and Health Disparities, the National Institute of Deafness and Other Communications Disorders, the National Institute of Dental and Craniofacial Research, the National Institute of Diabetes and Digestive and Kidney Diseases, the National Institute of Neurological Disorders and Stroke, and the Office of Dietary Supplements.


  • Arsenic
  • Dietary
  • Environmental
  • Hispanic/Latino
  • Urine

PubMed: MeSH publication types

  • Journal Article
  • Research Support, N.I.H., Extramural

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