Twenty-four hour urinary albumin excretion was measured using sensitive methods in 129 renal transplant donors 1 to 22 years (mean 7.3 years) after kidney donation. The 24 hour urinary albumin excretion values for the donor group was 6 ± 9.9 mg (mean ± standard deviation) (range of 0.1 to 65.2 mg) and was 7.7 ± 4.5 mg for the control group. Five donors (3.9 percent) had 24 hour urinary albumin excretion levels of 25.5 to 65.2 mg 6 to 13 years after donation, values that were greater than a single value from any member of the control group. Elevated diastolic blood pressure (90 mm Hg or greater) was present in these five donors, and in three, labile or established hypertension was present at the time of donation. It is likely that more careful screening of.
Bibliographical noteFunding Information:
From the Depmlments of Pediatrics and Surgery, University of Minnesota, Minneapolis, Minnesota. Suppoftsd in part by National Institutes of Health Gt'ants AM01014.A l10704.A M13083,A M25518.a nd AM28146.B ethesda, Maryland; Mlmmsota Medlcsl Four'~atlon Research Grant KRF t-80; and the Viking Ct~lldrens Ftmd, Minneapolis, Minnesota. Requests for reprints should be addressed to Blar¢~ Chavers, biD, De-parlment of Ped~h.k:s,~ of Minnesota, Box 491 Mayo, 420 Delaw'a'e Street SE, Minneapolis, Mfnneso~ 55455.