Upregulation of human glycolipid transfer protein (GLTP) induces necroptosis in colon carcinoma cells

Biochemistry, Genetics and Molecular Biology

• Colon 100%
• Upregulation 100%
• Mitochondrial Membrane Transport Protein 100%
• Necroptosis 100%
• Glycolipid 100%
• Carrier Protein 100%
• Sphingosine-1-Phosphate 27%
• Cell Death 27%
• Ceramide 27%
• Glycosphingolipid 27%
• Cell Cycle 18%
• Protein Kinases 18%
• Sphingolipid 18%
• Lipid 9%
• Oligomerization 9%
• Transport Protein 9%
• down Regulation 9%
• Binding Site 9%
• Cyclin E 9%
• Cell Cycle Progression 9%
• Chromosome 12 9%
• P21 9%
• Cell Membrane 9%
• Phosphotransferase 9%
• Kinase 9%
• Cyclin-Dependent Kinase 9%
• Cyclin-Dependent Kinase 2 9%
• Cyclin D1 9%
• Cyclin-Dependent Kinase 4 9%
• CDKN1B 9%
• Messenger RNA 9%
• Sphingomyelin 9%

Keyphrases

• Necroptosis 100%
• Colon Cancer Cells 100%
• Glycolipid Transfer Protein 100%
• Overexpressing 27%
• Glycosphingolipids 27%
• Cell Death 27%
• Protein Overexpression 27%
• HT-29 27%
• Ceramide 18%
• Protein Level 18%
• Cyclin-dependent Kinase Inhibitor 18%
• Sphingosine-1-phosphate 18%
• Receptor-interacting Protein Kinase 3 (RIPK3) 18%
• Cyclin-dependent Kinase 2 (CDK2) 9%
• Overexpression 9%
• Quiescence 9%
• Phosphorylation 9%
• Cyclin-dependent Kinase 4 (CDK4) 9%
• Cyclin D1 (CCND1) 9%
• Cell Cycle Progression 9%
• Lipid Transfer Protein 9%
• Sphingolipids 9%
• Oligomerization 9%
• Cyclin E 9%
• Binding Site 9%
• MRNA Level 9%
• Minimal Change 9%
• Chromosome 12 9%
• Cip1 9%
• Mixed Lineage Kinase 9%
• Sphingosine 9%
• Human Colon Carcinoma Cells 9%
• Sphingomyelin 9%
• HCT116 Cells 9%
• HCT116 9%
• Hexosylceramide 9%
• Colorectal Cancer Cells 9%
• Cytosolic Calcium 9%
• Biological Fate 9%
• Kip1 9%
• Ceramide-1-phosphate 9%
• Amphitropical 9%
• Sphingolipid Rheostat 9%
• Plasma Membrane Permeabilization 9%
• CCD-18Co 9%
• Mechanistic Studies 9%
• Protein Upregulation 9%