Unusual Aspects of Acute Q Fever-Associated Hepatitis

STEVEN H. YALE, PIET C. DE GROEN, JULIUS D. TOOSON, PAUL J. KURTIN

Research output: Contribution to journalArticle

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Abstract

We describe a 37-year-old farmer with a 3-week history of fevers and hepatitis, in whom Q fever was diagnosed. The diagnosis was based on the findings of characteristic “ring” granulomas on a bone marrow biopsy specimen and confirmed by complement-fixation antibody tests to Coxiella burnetii. Unusual aspects of this case included (1) relatively low complement-fixation antibody titers, (2) prolonged prothrombin time, (3) false-positive results of a serologic test for the human immunodeficiency virus (HIV), and (4) ring granulomas that progressed to atypical granulomas in biopsy specimens.

Original languageEnglish (US)
Pages (from-to)769-773
Number of pages5
JournalMayo Clinic Proceedings
Volume69
Issue number8
DOIs
StatePublished - Jan 1 1994
Externally publishedYes

Keywords

  • AIDS
  • ELISA
  • HIV
  • acquired immunodeficiency syndrome
  • enzyme-linked immunosorbent assay
  • human immunodeficiency virus

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