Skip to main navigation Skip to search Skip to main content

Unrelated donor allogeneic transplantation for adult acute lymphoblastic leukemia: A review

Research output: Contribution to journal › Review article › peer-review

Abstract

Acute lymphoblastic leukemia is highly sensitive to induction chemotherapy; however, long-term survival in adults has been less than 35%, primarily as a result of high relapse rate. Treatment for relapsed disease is even less successful. The optimal post-remission therapy in the first complete remission offers the best opportunity for leukemia-free survival. Allogeneic donor stem cell transplantation can offer a unique anti-leukemia effect and a potential for extended survival. We will discuss advances in unrelated donor (URD) stem cells transplantation, improvements in transplantation process and supportive care along with growing experience with umbilical cord blood (UCB) allografts.

Original languageEnglish (US)
Pages (from-to)455-464
Number of pages10
JournalBone marrow transplantation
Volume41
Issue number5
DOIs
StatePublished - Mar 2008

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Fingerprint

Dive into the research topics of 'Unrelated donor allogeneic transplantation for adult acute lymphoblastic leukemia: A review'. Together they form a unique fingerprint.

Cite this