Unrecognized myocardial infarction: Experience in the multiple risk factor intervention trial (MRFIT)

R. H. Grimm, S. Tillinghast, K. Daniels, J. D. Neaton, S. Mascioli, R. Crow, M. Pritzker, R. J. Prineas

Research output: Contribution to journalArticlepeer-review

63 Scopus citations

Abstract

Observation of serial electrocardiographic changes and review of hospital records are effective means of identifying nonfatal MI in a defined population followed prospectively. Collecting hospital records increases the number of nonfatal infarctions detected substantially. Although there is some overlap, the two methods identify different sets of nonfatal MIs. The incidence of 'silent myocardial infarction' in MRFIT compares closely with that previously reported in the Framingham Heart Study. Subsequent coronary heart disease mortality rates are similar regardless of whether the nonfatal MIs are identified by physician review of hospital records or by serial changes on the ECG.

Original languageEnglish (US)
Pages (from-to)II-6-II-8
JournalCirculation
Volume75
Issue number3 II SUPPL.
StatePublished - 1987

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